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Figure 4 | BMC Immunology

Figure 4

From: Serum reactome induced by Bordetella pertussis infection and Pertussis vaccines: qualitative differences in serum antibody recognition patterns revealed by peptide microarray analysis

Figure 4

3D-plots representing the differential mean index IgG recognition value in serum from whooping cough group. The mean index IgG value in the DT group was used as reference. This graph highlights proteins with high (A and B: filamentous hemagglutinin, FHA) and low (C: Bordetella resistance to killing, BrkA, Vag8 protein, Putative autotransporter, BapC) mean index values. This ’ landscape analysis’ aids to visualize the global recognition pattern of peptides recognized in serum samples from each group, it also allows to appreciate clear differences in the serum recognition pattern to Bp components in each test group. Note the strong recognition of Bp components to filamentous hemagglutinin, yet the relative decrease of antibody reactivities directed against the Vag8 protein and a factor which confers resistance to killing.

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BMC Immunology

ISSN: 1471-2172

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