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Figure 1 | BMC Immunology

Figure 1

From: Endogenous opioid inhibition of proliferation of T and B cell subpopulations in response to immunization for experimental autoimmune encephalomyelitis

Figure 1

Behavior of mice immunized with myelin oligodendrocytic protein (MOG) to induce EAE and treated with OGF or LDN. Behavioral scores of mice immunized with MOG33–55 and treated daily with either 10 mg/kg OGF (OGF) or 0.1 mg/kg naltrexone (LDN); control mice received intraperitoneal injections of 0.1 ml saline (saline). Mice were evaluated daily and scored (0–10 scale) by multiple observers, with one masked to treatment. Values represent means ± SEM; N = 5 or 6 mice/group. Significantly different from saline-injected mice at p < 0.05 (*).

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