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Table 1 Summary of found epitopes from the study from LTNP sera

From: Identifiable biomarker and treatment development using HIV-1 long term non-progressor sera

Epitope Epitope sequence Location in gp160 Sequence match
A QARLLLSGIVQQQMNLLRAT Start: AA 541 100% identical (100 out of 100)
End: AA 560
B GCSGKLICTTTVPWNASWSNKSL Start: AA 598 95.7-100% identical (20 of 100, 100%; 75 of 100, 95.7%); core epitope KLIC is 100%
End: AA 620
C LLELDKWASLWNWFDITNWLW Start: AA 661 100% identical (100 out of 100)
End: AA 681
D DITNWLWYIKI Start: AA 675 100% identical (100 out of 100)
End: AA 685
E WYIKIFIMIVGGLVGLRIVF Start: AA 681 90-100% identical (3 of 100, 90%; 82 of 100, 95%; 15 of 100, 100%)
End: AA 700
F PEGIEEEGGERDRDTRGRLV Start: AA 731 85-100% identical (8 of 100, 85%; 92 of 100, 100%)
End: AA 750
G IWVDLRSLFLFSYH Start: AA 757 92.9-100% identical (2 of 100, 92.9%; 98 of 100, 100%)
End: AA 770
CL3 GCSGKLICTT Start: AA 598 100% identical (100 out of 100)
End: AA 607
  1. 5 LTNP patients were assayed for 7 different epitopes and CL3 found to have a high degree of matching. The epitope, epitope sequence, epitope location within HIV-1 MN gp160, and the sequence match between the samples is given in the table.