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Fig. 3 | BMC Immunology

Fig. 3

From: Dexamethasone enhances programmed cell death 1 (PD-1) expression during T cell activation: an insight into the optimum application of glucocorticoids in anti-cancer therapy

Fig. 3

RU486 inhibits DEX-mediated increase of PD-1 expression. a Cells were cultured for 48 h in (a) medium (b) with 1 × 10−7 M DEX or (c) 1 × 10−7 M DEX plus 1 × 10−5 M RU486 for 48 h. Cells were stained with isotype control (cyan histograms) or PE-labeled anti-PD-1 antibody (red histograms). b Cells were cultured for 48 h with 1 × 10−7 M DEX or 1 × 10−7 M DEX plus different doses of RU486 or 1 × 10−7 M RU486 alone. Data is presented as the mean ± SEM of three experiments. *p < 0.05. **p < 0.01

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BMC Immunology

ISSN: 1471-2172

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