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Fig. 5 | BMC Immunology

Fig. 5

From: Dexamethasone enhances programmed cell death 1 (PD-1) expression during T cell activation: an insight into the optimum application of glucocorticoids in anti-cancer therapy

Fig. 5

Effects of HC on PD-1 expression in mouse T cells. a Activated mouse T cells were cultured in medium, HC (10−9, 10−7, 10−5 M) or HC (10−5 M) plus RU486 (10−5 M) for 48 h. Surface PD-1 expression was increased in a dose-dependent manner and this effect was inhibited by RU486. b PD-1 expression was increased in a dose-dependent manner both in CD4+ and CD8+ T cells. c Tem are more susceptible to HC-induced upregulation of PD-1. Data is presented as mean ± SEM of three experiments. **p < 0.01

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BMC Immunology

ISSN: 1471-2172

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