Fig. 4

β-Catenin regulation of iNKT2 and iNKT17 cells is maintained in the periphery. a Total cell numbers of iNKT1, iNKT2 and iNKT17 cells from control, β-CAT-cKO and β-CAT-Tg mice in spleen and liver (n = 3, mean ± sem). b Gating strategy for CD4⁺ IL-17RB⁺ iNKT cells is shown in left. Right, frequency of IL-4-expressing CD4⁺ IL-17RB⁺ iNKT cells from spleens of control and β-CAT-Tg mice 3 h after injection with PBS or 3 μg α-Galactosylceramide (αGC). * P < .05; ** P < .01; *** P < .001