Skip to main content
Fig. 5 | BMC Immunology

Fig. 5

From: Immunosenescence of the CD8+ T cell compartment is associated with HIV-infection, but only weakly reflects age-related processes of adipose tissue, metabolism, and muscle in antiretroviral therapy-treated HIV-infected patients and controls

Fig. 5

Unadjusted and adjusted associations between KLRG1+ and PD-1+CD8+ T cells and ageing parameters in HIV+. Age was adjusted for HIV-, ART-duration, and current ART; IL-6, suPAR, HOMA-IR, metabolic syndrome, VAT, and lLMI were adjusted for age, HIV-, ART-duration, and current ART. Parameters were transformed using log2(x). Estimates and 95 % CI are back transformed using (2β-1) × 100 and shown as percent change in the outcome per unit increase of the covariate. The dashed line marks an estimate change of 0 %. Abbreviations: HOMA-IR: homeostatic model assessment of insulin resistance; IL-6: interleukin-6; KLRG1: killer cell lectin-like receptor G1; lLMI: leg lean mass index; PD-1: programmed death-1; suPAR: soluble urokinase plasminogen activator receptor; VAT: visceral adipose tissue

Back to article page

BMC Immunology

ISSN: 1471-2172

Contact us