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Table 1 Extrapolation of classification models identified in adolescent CFS (Broderick et al., 2012) to adult pre and post-menopausal groups

From: Illness progression in chronic fatigue syndrome: a shifting immune baseline

Classification based on Stepwise model of IL-1α, 6,8,13,23 Consensus model of IL-6, 8, and 23 Minimal model of IL-6 and 8
(a) Training set: Age < =18 years
 Correct rate 0.93 0.86 0.79
 Error rate 0.07 0.14 0.21
 Sensitivity 0.94 0.89 0.78
 Specificity 0.92 0.83 0.79
 Positive predictive value 0.89 0.80 0.74
 Negative predictive value 0.96 0.91 0.83
(b) Test set: 18 < Age < = 50 years
 Correct rate 0.49 0.26 0.35
 Error rate 0.51 0.74 0.65
 Sensitivity 0.09 0.23 0.09
 Specificity 0.90 0.29 0.62
 Positive predictive value 0.50 0.25 0.20
 Negative predictive value 0.49 0.26 0.39
(c) Test set: Age > 50 years a
 Correct rate 0.46 0.29 0.39
 Error rate 0.54 0.71 0.61
 Sensitivity 0.00 0.32 0.14
 Specificity 0.93 0.25 0.64
 Positive predictive value 0.00 0.30 0.29
 Negative predictive value 0.48 0.27 0.43
  1. a n = 28 of 47 HC to match ME/CFS age and BMI