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Fig. 1 | BMC Immunology

Fig. 1

From: Double-stranded RNA analog and type I interferon regulate expression of Trem paired receptors in murine myeloid cells

Fig. 1

Deduced amino acid sequences of murine paired Trems, Treml7 and Treml8. Murine paired Trems and other mammalian Treml7 and Treml8 are aligned. Boxs indicate potential N-linked glycosylation sites predicted by NetNGlyc program (http://www.cbs.dtu.dk/services/NetNGlyc/). ‘#’ represents the ITIM, defined as (I/V/L/S)-X-Y-X-X-(L/V). ‘+’ represents the lysine residue in the transmembrane region (TM), which is presumed to be involved in the interaction with DAP12. SP, signal peptide; Ig, immunoglobulin; CPR, cytoplasmic region. Black shaded area, 100–90 % identity; gray shaded area, 89–70 % identity; light gray shaded area, 69–50 % identity. Mm; mouse (Mus musculus), Oc; rabbit (Oryctolagus cuniculus), Cf; dog (Canis lupus familiaris), Ec; horse (Equus caballus)

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