Fig. 1From: Double-stranded RNA analog and type I interferon regulate expression of Trem paired receptors in murine myeloid cellsDeduced amino acid sequences of murine paired Trems, Treml7 and Treml8. Murine paired Trems and other mammalian Treml7 and Treml8 are aligned. Boxs indicate potential N-linked glycosylation sites predicted by NetNGlyc program (http://www.cbs.dtu.dk/services/NetNGlyc/). ‘#’ represents the ITIM, defined as (I/V/L/S)-X-Y-X-X-(L/V). ‘+’ represents the lysine residue in the transmembrane region (TM), which is presumed to be involved in the interaction with DAP12. SP, signal peptide; Ig, immunoglobulin; CPR, cytoplasmic region. Black shaded area, 100–90 % identity; gray shaded area, 89–70 % identity; light gray shaded area, 69–50 % identity. Mm; mouse (Mus musculus), Oc; rabbit (Oryctolagus cuniculus), Cf; dog (Canis lupus familiaris), Ec; horse (Equus caballus)Back to article page