Skip to main content

Table 2 Statistical analysis of promiscuous peptides across every two supertypes

From: HLAsupE: an integrated database of HLA supertype-specific epitopes to aid in the development of vaccines with broad coverage of the human population

  A B C D E F G H I J K L M N O P Q R T U V W X
A -- 193 152 81 131 28 98 22 207 295 32 24 319 61          
B 9 -- 119 68 114 71 100 45 115 156 31 23 29 37   1     1    
C 3 4 -- 20 62 7 57 16 96 112 34 16 47 112      5 4 4 2 4
D 5 16 3 -- 44 8 10 12 48 58 8 6 101 7          
E 3 15 3 11 -- 71 58 20 134 227 21 8 14 16          
F   3    1 -- 65 6 19 79 7 6   25      1   1 1 1
G   3     1 -- 44 34 157 35 20 4 46          
H 1 2    1 1   -- 26 33 3 10 9        1    
I   1 1 2 2     -- 192 20 8 25 27          
J 1 2   3 3      -- 32 8 44 44      1   1   
K   3    2   2     -- 20 9 1          
L 4    5      1   1 -- 2 5          
M 10 1   2          -- 4          
N 2 1 3   1      1     --          
O    1          2    -- 192 99 200 310 168 270 285 265
P                2 -- 104 336 341 177 292 320 292
Q                1 3 -- 138 127 92 134 108 100
R            1     1 43 4 -- 476 234 402 403 380
T   19 2 10 5 1          9 17   26 -- 782 1714 1550 1310
U   9   4 1           6 7 1 9 53 -- 746 724 583
V   10 1 9 3           5 18 1 12 171 51 -- 1361 1088
W   6   1 1           7 8   13 93 38 71 -- 1089
X   2   2            5 10   1 87 7 32 34 --
  1. Promiscuous peptides that can be presented by multiple HLA molecules within different supertypes were collected, and a statistical analysis of these promiscuous data across every two supertypes was performed. Statistics on promiscuous epitopes are shown in the lower triangle, and statistics on promiscuous binding peptides are shown in the upper triangle. The values in the table indicate the numbers of peptides that can be presented by HLA molecules within the two supertypes indicated in the row and column headers. The supertype names are presented in capital letters according to the labels in Table 1