Fig. 3

Neutrophils and albumin are higher in BALF of cPLA₂α^−/− than cPLA₂α^+/+ mice during C. albicans infection. The number of (a) total cells, (b) alveolar macrophages and (c) neutrophils were determined in BALF (5 lavages) from cPLA₂α^−/− (KO, open symbols) and cPLA₂α^+/+ (WT, closed symbols) mice instilled with saline (Sal, squares) or 10⁶ C. albicans (CA, circles). d cPLA₂α^+/+ (WT) and cPLA₂α^−/− (KO) mice were lavaged 12 and 24 h after instillation of 10⁶ C. albicans or saline. Albumin levels were determined in BALF by ELISA. (n = 8-13 mice/group, from 4–6 independent experiments). *P < 0.05 compared to cPLA₂α^+/+ saline control; ^ϕ P < 0.05 compared to cPLA₂α^+/+ saline control, ^# P < 0.05 compared to cPLA₂α^−/− saline control; **P < 0.05 compared to cPLA₂α^+/+ with CA