Intranasal immunization with recombinant Toxoplasma gondii actin depolymerizing factor confers protective efficacy against toxoplasmosis in mice

Table 1 Splenocyte proliferative responses in immunized mice stimulated with rTgADF or ConA

Groups^a	Proliferation (Stimulation Index)^b
Groups^a	rTgADF	ConA
PBS	0.883 ± 0.0135	2.192 ± 0.1491
10 μg rTgADF	0.910 ± 0.0318	2.073 ± 0.1182
20 μg rTgADF	0.952 ± 0.0741	2.231 ± 0.1215
30 μg rTgADF	2.542 ± 0.1213*	2.284 ± 0.1743
40 μg rTgADF	2.391 ± 0.1912*	2.212 ± 0.1811

*P < 0.05 compared to the PBS group
^aSplenocytes from mice (n = 8 per group) intranasally immunized with PBS and different doses of rTgADF were harvested two weeks after the last immunization and stimulated with rTgADF or ConA
^bThe level of splenocyte proliferation is expressed as the stimulation index (SI). Results represent mean ± SD values of three independent experiments

ISSN: 1471-2172