Adverse events | Incidence (per 100 children) Vaccine dose | P-value (1st and 2nd dose comparison) | P-value (2nd and 3rddose comparison) | ||
---|---|---|---|---|---|
1st dose (2 months) N = 373 | 2nddose (4 months) N = 372 | 3rddose (6 months) N = 374 | |||
Swelling | 79(21.2) | 50(13.4) | 48(12.8) | 0.003 | 0.068 |
Redness | 50(13.4) | 30(8.1) | 43(11.5) | 0.026 | 0.679 |
Pain | 190(50.9) | 143(38.4) | 62(16.6) | 0.001 | 0.162 |
Mild fever | 45(12.1) | 33(8.9) | 63(16.8) | 0.068 | <0.001 |
High fever | 1(0.3) | 0(0) | 0(0) | 0.388 | NA |
Drowsiness | 83(22.3) | 72(19.4) | 70(18.7) | 0.310 | 0.725 |
Anorexia | 65(17.4) | 51(13.7) | 52(13.9) | 0.126 | 1 |
Restlessness | 35(9.4) | 115(30.9) | 119(31.8) | <0.001 | 0.766 |
Vomiting | 16(4.3) | 19(5.1) | 17(4.5) | 0.510 | 0.510 |
Long-term crying | 24(6.4) | 16(4.3) | 22(5.9) | 0.210 | 0.510 |
Encephalopathy | 0(0) | 0(0) | 0(0) | NA | NA |
Convulsion | 0(0) | 0(0) | 0(0) | NA | NA |
History of convulsion | 0(0) | 1(0.3) | 2(0.5) | 0.387 | 0.488 |
Family history of convulsion | 0(0) | 14(3.8) | 6(1.6) | <0.001 | 0.074 |