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Table 1 The thermodynamic and kinetic constants for CCR3 binding with different ligands

From: Functional expression of CCL8 and its interaction with chemokine receptor CCR3

Agonists

k a(M−1 s−1)

k d(s−1)

K D (M)

CCL8

8.6 × 104

0.00106

1.2 × 10−7

CCL11a

2.0 × 105

0.0740

3.7 × 10−7

CCL24a

6.3 × 105

0.1900

3.0 × 10−7

  1. aData were taken from (Wang et al. [22])