Fig. 5From: Monoclonal antibody against EV71 3Dpol inhibits the polymerase activity of RdRp and virus replicationKaplan-Meier analysis of antiviral efficacy of EV71 3Dpol-specific mAbs on ICR neonatal mice. a A neonatal mouse infected with EV71/MAV-VR exhibited limb paralysis (indicated by arrows). The virus inoculated mice were monitored daily for (b) clinical score and (c) survival for a period of 16 days. Clinical scores were graded as follows: 0, healthy; 1, reduced mobility; 2, limb weakness; 3, paralysis; 4, death. The number of mice in each group were indicated in one bracketBack to article page