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Fig. 5 | BMC Immunology

Fig. 5

From: Monoclonal antibody against EV71 3Dpol inhibits the polymerase activity of RdRp and virus replication

Fig. 5

Kaplan-Meier analysis of antiviral efficacy of EV71 3Dpol-specific mAbs on ICR neonatal mice. a A neonatal mouse infected with EV71/MAV-VR exhibited limb paralysis (indicated by arrows). The virus inoculated mice were monitored daily for (b) clinical score and (c) survival for a period of 16 days. Clinical scores were graded as follows: 0, healthy; 1, reduced mobility; 2, limb weakness; 3, paralysis; 4, death. The number of mice in each group were indicated in one bracket

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