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Fig. 5 | BMC Immunology

Fig. 5

From: Active immunization with norovirus P particle-based amyloid-β chimeric protein vaccine induces high titers of anti-Aβ antibodies in mice

Fig. 5

Detection of anti-Aβ antibodies by ELISA and determination of Aβ-specific T cell responses by ELISPOT (a) Serum antibody concentrations of mice immunized four times with four types of Aβ1–6 chimeric protein vaccines were detected by ELISA. Serum antibody concentrations were relatively determined according to the standard curve based on 6E10. (b) Spleen cells isolated from immunized mice were stimulated with Aβ1–42 peptide. (c) Spleen cells were stimulated with wild-type NoV P particles. **P < 0.01, ***P < 0.001, NS = no significant difference

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BMC Immunology

ISSN: 1471-2172

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