Table 1 Mean value of biomarkers, analytical (CVA), intra-individual (CVI), and inter-individual (CVG) components of variation for eighteen serum biomarkers
Weighted | CV I (%) | CV G (%) | |||||||
|---|---|---|---|---|---|---|---|---|---|
Biomarker (unit) | Mean | CV A (%) | Male | Female | Both | Male | Female | Both | |
Group I | IL-1β (pg/mL) | 0.157 | 4.0a | 38.0 | 22.0 | 30.9 | NCb | 42.0 | 27.0 |
IL-6 (pg/mL) | 0.961 | 6.4 | 23.0 | 20.0 | 21.5 | 33.0 | 19.0 | 26.4 | |
IL-1Ra (pg/mL) | 419.0 | 6.0 | 15.0 | 17.3 | 17.0 | 42.0 | 37.7 | 43.0 | |
IFN-γ (U/L) | 278 | 13.5 | 29.0 | 34.0 | 31.0 | 10.8 | 33.0 | 22.0 | |
TNF-α (pg/ml) | 12.63 | 8.2 | 7.9 | 14.2 | 12.7 | 24.3 | 31.7 | 27.2 | |
Group II | IL-8 (pg/mL) | 12.16 | 3.5a | 24.0 | 61.6 | 51.4 | 32.0 | 28.0 | 30.2 |
MIP-1β (pg/mL) | 101.0 | 4.5 | 18.0 | 22.0 | 20.0 | 22.0 | 82.0 | 57.0 | |
RANTES (ng/mL)) | 32.71 | 3.2 | 27.0 | 23.0 | 24.0 | 51.0 | 30.0 | 39.0 | |
Group III | Adiponectin (μg/mL) | 6.29 | 3.7 | 12.0 | 17.0 | 15.9 | 49.0 | 42.0 | 48.1 |
Leptin (ng/mL) | 7.66 | 7.1 | 18.0 | 31.0 | 31.0 | 66.0 | 50.0 | 68.0 | |
Group IV | sCD14 (ng/mL) | 1435.0 | 2.8 | 8.8 | 7.6 | 8.0 | 16.0 | 6.1 | 11.4 |
sCD40L (ng/mL) | 6.02 | 3.0 | 14.5 | 12.7 | 13.2 | 18.4 | 12.8 | 14.6 | |
sCD163 (ng/mL) | 543.0 | 9.5 | 6.8 | 6.5 | 9.0 | 64.9 | 50.2 | 53.8 | |
sgp130 (ng/mL) | 281.0 | 4.8 | 4.4 | 7.5 | 7.0 | 12.5 | 10.4 | 15.0 | |
sIL-2Rα (pg/mL) | 796.0 | 3.6 | 9.0 | 19.0 | 15.1 | 34.0 | 49.0 | 41.7 | |
sIL-6R (ng/mL) | 31.77 | 3.0a | 18.2 | 12.9 | 16.3 | 18.5 | 18.9 | 20.3 | |
sTNF-RII (ng/mL) | 2.17 | 10.1 | 17.6 | 15.8 | 17.4 | 36.0 | 25.9 | 28.9 | |
Group V | Neopterin (nmol/L) | 5.20 | 6.4 | 14.5 | 64.0 | 35.0 | 69.4 | 14.0 | 37.0 |