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Table 2 Mean value lymphocyte phenotype, analytical (CVA), intra-individual (CVI), and inter-individual (CVG) components of variation for five lymphocyte phenotypes

From: Biological variation of immunological blood biomarkers in healthy individuals and quality goals for biomarker tests

Biomarker

Weighted Mean (%)

CV A (%)

Intra-subject variation

CV I (%)

Inter-subject variation CVG (%)

Phenotype

  

Male

Female

Both

Male

Female

Both

CD3 (T cells)

73

1.0

3.0

4.1

3.6

8.3

13.6

10.8

CD4

46

3.2

6.8

5.6

6.1

10.5

20.9

20.7

CD8

25

2.4

6.9

5.7

6.7

20.3

43.6

35.5

CD19 (B cells)

12

4.1

22.0

12.6

17.4

27.4

37.0

31.9

CD56/16 (NK cells)

13

5.8

21.4

24.9

23.0

23.4

50.9

37.1

  1. CVA is analytical variation (mean CV of daily QC run for 20 days) expressed as a %CV