Fig. 1

Interleukin (IL)-35 concentration in the plasma and IL-35 receptor mRNA relative level in CD14⁺ monocytes in patients with Kawasaki disease (n = 33) and controls (n = 17). Plasma IL-35 concentration was measured by enzyme linked immunosorbent assay. mRNA corresponding to IL-35 receptor subunits, including IL-12Rβ2 and gp130, in purified CD14⁺ monocytes were semi-quantified by real-time reverse transcriptional polymerase chain reaction. a IL-35 concentration was elevated in the plasma from patients with Kawasaki disease when compared with controls. There were no significant differences of (b) IL-12Rβ2 or (c) gp130 mRNA relative level between patients with Kawasaki disease and controls. Student’s t test was used for comparison. Individual level of each subject was shown. The horizon line presented mean, and error bar presented standard deviation