Table 2 Geometric mean titre (GMT) of anti-CT IgG, anti-CT IgA and vibriocidal antibodies elicited in rabbits vaccinated with either the LACV or unformulated VCUSM14P
Immune response (n = 3) | GMT (range) on week | |||||
|---|---|---|---|---|---|---|
Pre | First | Second | Third | Fourth | ||
Anti-CT IgG | LACV | 10.00 (10) | 17.12 (16–22) | 697.17 (531–829) | 1585.87 (1270–2307) | 2754.71 (2351–3191) |
Unformulated VCUSM14P | 10.00 (10) | 15.44 (12–18) | 162.66 (138–182) | 382.00 (375–387) | 646.18 (610–712) | |
Anti-CT IgA | LACV | 10.00 (10) | 72.67 (65–78) | 94.87 (88–100) | 129.00 (114–151) | 150.95 (143–161) |
Unformulated VCUSM14P | 10.00 (10) | 67.39 (61–73) | 77.77 (63–86) | 86.78 (85–90) | 79.82 (64–90) | |
Vibriocidal antibody | LACV | 10.00 (10) | 40.00 (40) | 153.03 (140–160) | 156.59 (150–160) | 316.42 (300–330) |
Unformulated VCUSM14P | 10.00 (10) | 40.00 (40) | 139.04 (120–160) | 149.30 (130–160) | 145.37 (120–160) | |