Fig. 1

Elevated frequency of CXCR5⁺CD4⁺ Tfh cells in the peripheral blood of patients with acute MeV infection. a The frequency of CXCR5⁺CD4⁺ Tfh cells with an ICOS^high and PD-1^high phenotype in PBMCs from the patients with MeV infection was detected using flow cytometry; b CXCR5⁺CD4⁺ Tfh cells in the patients with MeV infection; c ICOS^highCXCR5⁺CD4⁺ Tfh cells in the patients with MeV infection; d PD-1^highCXCR5⁺ Tfh cells in the patients with MeV infection. The horizontal lines represent the means. ***, P < 0.0001