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Table 2 Differential expression analysis of top 50 miRNAs in HIV-positive (n = 12) versus HIV-negative (n = 8) subjects from the test cohort

From: Small RNA sequencing of extracellular vesicles identifies circulating miRNAs related to inflammation and oxidative stress in HIV patients

  baseMean Log2 FC P value P adj
hsa-miR-26a-5p 620 −0.106 0.8216 0.9831
hsa-miR-148a-3p 514.38 0.798 0.2256 0.6636
hsa-miR-21-5p* 493.5 −0.405 0.4709 0.981
hsa-let-7i-5p 318.91 −0.191 0.7614 0.9831
hsa-miR-122-5p* 288.3 0.953 0.4941 0.9831
hsa-miR-1-3p 243.23 0.662 0.6196 0.9831
hsa-let-7a-5p* 224.95 1.512 0.0699 0.3493
hsa-let-7f-5p 216.84 −1.594 0.1263 0.4859
hsa-miR-423-5p* 210.36 0.239 0.8054 0.9831
hsa-let-7b-5p 181.67 1.098 0.2963 0.7134
hsa-miR-126-3p 134.04 3.067 0.0056 0.1169
hsa-let-7 g-5p 113.18 −0.108 0.9161 0.9831
hsa-let-7c-5p 109.04 2.39 0.0466 0.259
hsa-miR-30d-5p 102.88 −1.677 0.2039 0.6371
hsa-miR-99a-5p 96.3 0.527 0.6449 0.9831
hsa-miR-92a-3p 86.99 0.779 0.4643 0.981
hsa-miR-10a-5p* 83 2.9 0.0213 0.1779
hsa-miR-100-5p 80.05 1.389 0.2811 0.7134
hsa-miR-22-3p 79.59 2.307 0.0898 0.3743
hsa-miR-143-3p 73.61 1.308 0.3139 0.7134
hsa-miR-486-5p 69.46 1.373 0.3024 0.7134
hsa-miR-1246 64.35 −2.662 0.0342 0.2441
hsa-miR-155-5p 64.01 −0.322 0.7998 0.9831
hsa-miR-151a-3p 59.85 −0.261 0.8725 0.9831
hsa-miR-7-5p 57.03 0.038 0.9751 0.9917
hsa-miR-99b-5p 51.54 −0.933 0.7672 0.9831
hsa-miR-27a-3p 50.45 1.684 0.1728 0.5761
hsa-miR-320a 50.4 0.352 0.811 0.9831
hsa-miR-30c-5p 49.92 −1.558 0.2631 0.7134
hsa-let-7d-5p 44.98 2.287 0.0391 0.2447
hsa-miR-101-3p 44.39 −0.6 0.674 0.9831
hsa-miR-192-5p 41.22 2.429 0.0795 0.3615
hsa-miR-222-3p 41.18 0.194 0.8841 0.9831
hsa-miR-199a-3p 40.5 0.08 0.9438 0.9831
hsa-miR-199b-3p 40.5 0.08 0.9438 0.9831
hsa-miR-10b-5p 34.17 0.197 0.8896 0.9831
hsa-miR-181a-5p 33.66 −5.884 1.59E-05 0.0008
hsa-miR-27b-3p* 31.04 2.583 0.0112 0.1169
hsa-miR-26b-5p 30.29 0.012 0.9917 0.9917
hsa-miR-378a-3p 29.32 3.691 0.0117 0.1169
hsa-miR-24-3p 28.94 1.696 0.1589 0.5674
hsa-miR-191-5p 28.19 −0.71 0.676 0.9831
hsa-miR-25-3p 25.4 0.235 0.8851 0.9831
hsa-miR-125a-5p 22.86 −4.3 0.0104 0.1169
hsa-miR-451a 22.8 0.443 0.7961 0.9831
hsa-miR-146a-5p* 22.33 0.856 0.5596 0.9831
hsa-miR-125b-5p* 14.62 −0.665 0.6723 0.9831
hsa-miR-218-5p 14.38 1.004 0.5147 0.9831
hsa-miR-423-3p 12.6 0.485 0.7753 0.9831
hsa-miR-30a-5p 10.24 −0.284 0.8542 0.9831
  1. * miRNAs selected for qRT-PCR validation are indicated with an asterisk. Significant raw p-values are in bold