Fig. 7

D-mannose ameliorates lupus phenotypes in B6/lpr mice. Four month old B6.lpr mice were treated with D-mannose in drinking water for 10 weeks. a. Serum anti-dsDNA IgG. Frequency of T_N (b) and Treg cells (c). d. CD44 MFI on CD4⁺ T cells. e. T_FH /T_FR ratio in spleen and mLN. f. CD206 MFI on spleen cDCs. Mean ± S.E.M of n = 4 per group compared with t tests. *: p < 0.05