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Fig. 2 | BMC Immunology

Fig. 2

From: Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation

Fig. 2

MyD88, TLR2 and TLR7 colocalize with Bb in phagosomes. a-c Confocal 40x images and colocalization analysis of internalized Bb with MyD88 (a), TLR2 (b) or TLR7 (c) in WT BMDMs after stimulation at MOI 10:1. White box indicates phagosome depicted in inset. Large inset in (b) shows coiling pseudopod formation around Bb on cell surface. Graph shows the intensity of each indicated pixel marker across the white line (distance on x-axis). Green is Bb, blue is MyD88 (a), TLR2 (b) or TLR7 [7], and red is actin

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BMC Immunology

ISSN: 1471-2172

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