Table 1 Clinical parameters of RA and HCs
Characteristics | RA (n = 81) | HCs (n = 53) | P value | RA patients(n = 81) | P value | ||
|---|---|---|---|---|---|---|---|
BMI < 18.5 (n = 17) | 18.5 ≤ BMI ≤ 25 (n = 47) | BMI > 25 (n = 17) | |||||
Demographics | |||||||
Age, mean ± SE, years | 50.0 ± 1.6 | 53.3 ± 2.8 | 0.67 | 41.6 ± 3.9 | 52.5 ± 2.1 | 52.1 ± 2.6 | 0.64 |
Sex (F/M) | 72/9 | 50/3 | 0.88 | 18/1 | 41/5 | 13/3 | 0.54 |
Lipid profiles | |||||||
TC, mean ± SE, mmol/L | 4.3 ± 0.1 | 4.2 ± 0.3 | 0.74 | 3.9 ± 0.2 | 4.4 ± 0.1 | 4.4 ± 0.3 | 0.13 |
TG, mean ± SE, mmol/L | 1.1 ± 0.07 | 0.8 ± 0.1 | 0.55 | 0.8 ± 0.06 | 1.1 ± 0.1 | 1.3 ± 0.2 | 0.087 |
HDL-C, mean ± SE, mmol/L | 1.2 ± 0.04 | 1.3 ± 0.02 | 0.34 | 1.2 ± 0.08 | 1.2 ± 0.07 | 1.0 ± 0.07 | 0.03 |
LDL-C, mean ± SE, mmol/L | 2.6 ± 0.08 | 2.5 ± 0.1 | 0.48 | 2.3 ± 0.1 | 2.6 ± 0.1 | 2.9 ± 0.2 | 0.080 |
Apoplipoprotein A1, mean ± SE, g/L | 1.3 ± 0.03 | 1.3 ± 0.05 | 0.93 | 1.3 ± 0.08 | 1.3 ± 0.05 | 1.2 ± 0.07 | 0.82 |
Apoplipoprotein B, mean ± SE, g/L | 0.8 ± 0.02 | 0.9 ± 0.01 | 0.81 | 0.7 ± 0.04 | 0.8 ± 0.03 | 0.9 ± 0.07 | 0.015 |
Disease characteristics | |||||||
ESR, mean ± SE, mm/h | 56.8 ± 4.5 | – | 56.7 ± 11.1 | 54.2 ± 6.1 | 63.1 ± 13.3 | 0.68 | |
CRP, mean ± SE, mg/L | 38.2 ± 5.0 | – | 40.4 ± 11.8 | 27.0 ± 4.3 | 55.8 ± 19.5 | 0.77 | |
TJC, mean ± SE | 8 ± 0.1 | – | 7 ± 0.1 | 9 ± 0.2 | 9 ± 0.1 | 0.81 | |
SJC, mean ± SE | 8 ± 0.2 | – | 7 ± 0.3 | 8 ± 0.2 | 9 ± 0.3 | 0.86 | |
DAS28-ESR, mean ± SE | 5.9 ± 0.2 | – | 5.5 ± 0.7 | 5.8 ± 0.3 | 6.0 ± 0.5 | 0.09 | |
RF titers, mean ± SE, IU/mL | 226.4 ± 41.5 | – | 331.1 ± 75.2 | 262.2 ± 63.2 | 113.6 ± 41.38 | 0.06 | |
ACPA titers, mean ± SE, U | 281.5 ± 14.9 | – | 279.1 ± 41.1 | 306.3 ± 20.4 | 256.3 ± 44.8 | 0.88 | |