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Table 4 Associations of adiponectin levels in SVR patients at 24 weeks post-therapy

From: Critical role of triglycerides for adiponectin levels in hepatitis C: a joint study of human and HCV core transgenic mice

24-week post-therapy factors Univariate analyses Multivariate analyses
  95% CI of β (β) p values 95% CI of β (β) p values
Male, yes − 1.708 to − 0.548(− 1.128)  < 0.001 − 1.89 to − 0.5 (− 1.195) 0.001
Age, (years) − 0.01 to 0.037 (0.013) 0.252   
BMI (kg/m2) − 0.183 to 0.136 (− 0.11) 0.004 − 0.139 to 0.16 (− 0.039) 0.443
ALT (U/L) − 0.042 to − 0.003 (− 0.023) 0.024 − 0.04 to 0.004 (− 0.018) 0.112
eGFR (mL/min/1.73 m2) − 0.024 to − 0.005 (− 0.015) 0.002 − 0.02 to − 0.001(− 0.011) 0.034
TG (mg/dL) − 0.008 to − 0.001 (− 0.005) 0.007 − 0.005 to 0.002 (− 0.002) 0.385
TC (mg/dL) − 0.005 to 0.011 (0.003) 0.418   
HOMA-IR − 0.153 to 0.045 (− 0.054) 0.283   
Uric acid (mg/dL) − 0.326 to 0.047 (− 0.14) 0.141   
NLR − 0.216 to 0.334 (0.059) 0.673   
Platelet (103/uL) − 0.01 to 0.00 (− 0.005) 0.039   
Liver cirrhosis, yes − 0.91 to 0.484 (− 0.213) 0.548   
Fibrosis-4 score 0.026 to 0.265 (0.146) 0.017 − 0.044 to 0.197 (21.72) 0.077
Ferritin (ng/mL) − 0.001 to 0.001 (0.000) 0.904   
IFNL3-rs12979860
CC genotype, yes
− 0.502 to 1.038 (0.268) 0.494   
  1. SVR: sustained virological response; BMI: body mass index; HCV: hepatitis C virus; RNA: ribonucleic acid; ALT: alanine transaminase; eGFR: estimated glomerular filtration rate; TG: triglycerides; TC: total cholesterol; HOMA-IR: homeostatic model assessment for insulin resistance; NLR: neutrophil lymphocyte ratio; IFNL3; interferon-λ3