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Table 4 Associations of adiponectin levels in SVR patients at 24 weeks post-therapy

From: Critical role of triglycerides for adiponectin levels in hepatitis C: a joint study of human and HCV core transgenic mice

24-week post-therapy factors

Univariate analyses

Multivariate analyses

 

95% CI of β (β)

p values

95% CI of β (β)

p values

Male, yes

− 1.708 to − 0.548(− 1.128)

 < 0.001

− 1.89 to − 0.5 (− 1.195)

0.001

Age, (years)

− 0.01 to 0.037 (0.013)

0.252

  

BMI (kg/m2)

− 0.183 to 0.136 (− 0.11)

0.004

− 0.139 to 0.16 (− 0.039)

0.443

ALT (U/L)

− 0.042 to − 0.003 (− 0.023)

0.024

− 0.04 to 0.004 (− 0.018)

0.112

eGFR (mL/min/1.73 m2)

− 0.024 to − 0.005 (− 0.015)

0.002

− 0.02 to − 0.001(− 0.011)

0.034

TG (mg/dL)

− 0.008 to − 0.001 (− 0.005)

0.007

− 0.005 to 0.002 (− 0.002)

0.385

TC (mg/dL)

− 0.005 to 0.011 (0.003)

0.418

  

HOMA-IR

− 0.153 to 0.045 (− 0.054)

0.283

  

Uric acid (mg/dL)

− 0.326 to 0.047 (− 0.14)

0.141

  

NLR

− 0.216 to 0.334 (0.059)

0.673

  

Platelet (103/uL)

− 0.01 to 0.00 (− 0.005)

0.039

  

Liver cirrhosis, yes

− 0.91 to 0.484 (− 0.213)

0.548

  

Fibrosis-4 score

0.026 to 0.265 (0.146)

0.017

− 0.044 to 0.197 (21.72)

0.077

Ferritin (ng/mL)

− 0.001 to 0.001 (0.000)

0.904

  

IFNL3-rs12979860

CC genotype, yes

− 0.502 to 1.038 (0.268)

0.494

  
  1. SVR: sustained virological response; BMI: body mass index; HCV: hepatitis C virus; RNA: ribonucleic acid; ALT: alanine transaminase; eGFR: estimated glomerular filtration rate; TG: triglycerides; TC: total cholesterol; HOMA-IR: homeostatic model assessment for insulin resistance; NLR: neutrophil lymphocyte ratio; IFNL3; interferon-λ3