Fig. 2
Effect of IL-15 D8SQ108S on the proliferation of CTLL-2 cells. a CTLL-2 cells (5 × 103 cells/well) were cultured for 72 h with serial dilutions 1:2 of IL-15 D8SQ108S or commercial huIL-15 with a starting concentration of 12 ng/mL, b CTLL-2 cells were cultured with 600 pg/mL of huIL-15 plus serial dilutions 1:2 of IL-15 D8SQ108S (initial concentration 6 ng/mL). Cell proliferation was measured by MTT staining. Data represent the mean values of OD578nm ± standard deviation from two independent experiments performed in triplicate. Dashed lines represent the minimum and maximum proliferation of the cells