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Fig. 3 | BMC Immunology

Fig. 3

From: A novel 4 immune-related genes as diagnostic markers and correlated with immune infiltrates in major depressive disorder

Fig. 3

Construction of the diagnostic risk model. A Screening of the optimal parameter (using lambda.1se as the best lambda) at which the vertical lines were drawn. B LASSO coefficient profiles of the 9 differentially expressed IRGs. C Boxplots of 9 IRGs expression level in the MDD and healthy controls. D Correlation heat map of 9 differentially expressed IRGs. The size of the colored squares represents the strength of the correlation; blue represents a negative correlation, and red represents a positive correlation. The darker the color is, the stronger correlation is. E Multivariate logistic regression determined independent candidate diagnostic biomarkers. F ROC analysis showing that this diagnostic model has good diagnostic performance. Statistical analysis was performed using the Mann–Whitney U test

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BMC Immunology

ISSN: 1471-2172

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