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Fig. 5 | BMC Immunology

Fig. 5

From: Antibody attributes that predict the neutralization and effector function of polyclonal responses to SARS-CoV-2

Fig. 5

Experimental validation of IgM-mediated neutralization. A. Median fluorescent intensity (MFI) levels of RBD-specific IgG, IgA, IgM observed pre- (filled circles) and post- (hollow squares) IgM depletion. Mean fold change in MFI across samples for each isotype is indicated below the figure. B. Neutralization titers pre- and post-IgM depletion. C. Comparison of RBD-specific Ig levels to neutralization titer. Statistical significance (two-tailed p value) of Spearman correlation coefficients reported in inset

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BMC Immunology

ISSN: 1471-2172

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