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Fig. 1 | BMC Immunology

Fig. 1

From: Helios expressing regulatory T cells are correlated with decreased IL-2 producing CD8 T cells and antibody diversity in Mozambican individuals living chronically with HIV-1

Fig. 1

Correlation between activated T cells and viral loads in PLWH. PBMC from PLWH (18) without viral suppression, PLWH-C (11) and PLWH-E (7). PBMC were stained with monoclonal antibodies and analyzed by eight-color flow cytometer. Viral loads were determined by a clinically validated in vitro nucleic acid amplification test for the quantitation of HIV-1 RNA in human plasma as described in Methods section (a) Correlation between the viral loads and proportion of CD8 T cells co-expressing CD38 and HLA-DR in PLWH without VS. Correlation between the proportion of CD8 T cells expressing IFNγ with viral loads (b) and CD4 T cell counts (c) in PLWH without VS. Spearman’s correlation r and p-values are indicated (***p < 0.0001)

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