Fig. 3
From: Exhausted phenotype of circulating CD8+ T cell subsets in hepatitis B virus carriers
Enhanced expression of inhibitory receptors on Tfc cells in HBV carriers. A Flow cytometric detection of PD1, TIM3, LAG3, and CTLA4 on Tfc and Tc/Treg cells in HBV carriers; B–E differential expression of PD1, TIM3, LAG3, and CTLA4 on Tfc, Tc, and Treg cells in HBV carriers. Tfc: follicular cytotoxic T cell (CXCR5+CD25−); Treg: regulatory T cell (CXCR5−CD25+); Tc: cytotoxic T cell (CXCR5−CD25−); HCs: healthy controls (n = 23), HBV: hepatitis B virus carriers (n = 31); data are presented as the means ± SEs; **P < 0.01; ††P < 0.01, Tfc versus Treg; ++P < 0.01, Tfc versus Tc; +P < 0.05, Tfc versus Tc