Table 6 Homozygous and heterozygous genotype of HLA-DRB1 epitopes associated with OBI

Gln^4β/Gln^4β

10 (9.35)

13 (4.64)

0.899–4.986

Gln^4β/Arg^4β

56 (52.34)

105 (37.50)

1.167–2.870

Arg^4β/Arg^4β

41 (38.32)

162 (57.86)

0.287–0.714

P9

Ala^57β/Asp^57β

2 (1.87)

9 (3.21)

0.122–2.699

Ala^57β/Ser^57β

0 (0.00)

5 (1.79)

1.002–1.034

Ala^57β/Val^57β

1 (0.93)

7 (2.50)

0.045–3.026

Asp^57β/Asp^57β

10 (9.35)

58 (20.71)

0.194–0.804

Asp^57β/Ser^57β

7 (6.54)

32 (11.43)

0.232–1.269

Asp^57β/Val^57β

56 (52.34)

114 (40.71)

1.021–2.503

Ser^57β/Ser^57β

1 (0.93)

3 (1.07)

0.090–8.467

Ser^57β/Val^57β

6 (5.61)

20 (7.14)

0.301–1.979

Val^57β/Val^57β

24 (22.43)

32 (11.43)

1.249–4.021

P9

His^60β/Ser^60β

1 (0.93)

7 (2.50)

0.045–3.026

His^60β/Tyr^60β

2 (1.87)

14 (5.00)

0.081–1.620

Ser^60β/Ser^60β

24 (22.43)

32 (11.43)

1.249–4.021

Ser^60β/Tyr^60β

61 (57.01)

134 (47.86)

0.922–2.263

Tyr^60β/Tyr^60β

19 (17.76)

93 (33.21)

0.249–0.756

P4

Val^78β/Val^78β

10 (9.35)

13 (4.64)

0.899–4.986

Tyr^78β/Tyr^78β

42 (39.25)

162 (57.86)

0.299–0.742

Val^78β/Tyr^78β

55 (51.40)

105 (37.50)

1.124–2.764