Fig. 1
From: Immunological characteristics of MAV/06 strain of varicella-zoster virus vaccine in an animal model
Evaluation of cross reactivity of antibodies induced by MAV/06 vaccine. Guinea pig (n = 30) were immunized subcutaneously two times at three weeks’ interval with MAV/06 vaccine. Sera were collected by cardiac puncture 3 weeks after second immunization. A PRNT50 titer against multiple VZV isolates (included genetic clade 1–5) were measured by plaque reduction neutralization assay in triplicate. Data are presented as means and standard deviations. B FAMA, which is the gold standard method to detect protective antibody against VZV, were performed once with MRC-5 cell infected with multiple VZV isolates