Table 1 Demographics and clinical characteristics of influenza patients
|  | Total (N = 61) | Moderate (N = 34) | Severe (N = 27) | P value |
|---|---|---|---|---|
Gender | Â | Â | Â | 0.4904 |
 Female | 29 (48%) | 18 (53%) | 11 (41%) |  |
 Male | 32 (52%) | 16 (47%) | 16 (59%) |  |
Age/years (mean (SD)) | 55.68 (14.71) | 59.00 (11.23) | 51.51 (17.51) | 0.0607 |
Flu virus strains | ||||
Influenza type A | 41 (67%) | 25 (74%) | 16 (59%) | 0.1195 |
Influenza type B | 18(30%) | 7(20%) | 11(41%) | Â |
Influenza type A & B | 2 (3%) | 2 (6%) | 0 (0%) | Â |
Comorbidity | ||||
Pneumonia disease | 50 (82%) | 23 (67%) | 27 (100%) | 0.0007 |
Cancer | 3 (5%) | 3 (8%) | 0 (0%) | 0.2475 |
Hypertension | 19 (31%) | 12 (35%) | 7 (26%) | 0.6125 |
Diabetes | 14 (23%) | 6 (17%) | 8 (30%) | 0.4243 |
Laboratory tests (mean (SD)) | ||||
Total leukocytes (× 109/L) | 9.96 (7.84) | 7.26 (5.28) | 12.66 (9.07) | 0.0012 |
Neutrophil (× 109/L) | 8.34 (7.49) | 5.51 (4.91) | 11.18 (8.58) | 0.0000 |
Proportion of Neutrophil (%) | 79.15 (12.61) | 71.77 (12.82) | 86.53 (6.84) | 0.0000 |
Lymphocytes (× 109/L) | 1.00 (0.56) | 1.04 (0.55) | 0.96 (0.57) | 0.4585 |
Proportion of Lymphocytes (%) | 13.14 (9.26) | 17.42 (10.40) | 8.86 (5.35) | 0.0003 |
Respiratory support | ||||
Extracorporeal membrane oxygenation | 12 (20%) | 0 (0%) | 12 (44%) | 0.0000 |
Invasive mechanical ventilation | 27 (44%) | 0 (0%) | 27 (100%) | 0.0000 |
Noninvasive mechanical ventilatory support | 29 (48%) | 16 (47%) | 13 (48%) | 1.0000 |
Require supplemental oxygen | 51 (84%) | 24 (71%) | 27 (100%) | 0.0015 |
Outcome | ||||
Hospitalization | 61 (100%) | 34 (100%) | 27 (100%) | 0.3701 |
Admission to ICU | 35 (57%) | 9 (26%) | 26 (96%) | 0.0000 |
Death | 14 (23%) | 0 (0%) | 14 (52%) | 0.0000 |