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Fig. 3 | BMC Immunology

Fig. 3

From: GBP2 acts as a member of the interferon signalling pathway in lupus nephritis

Fig. 3

a Enrichment analysis of differential immune-related genes using DAVID software, with the top 8 biological pathways selected based on enrichment scores, shown using bubble plots. Pā€‰<ā€‰0.05 is statistically significant. b Enrichment analysis of differential immune-associated genes using Funrich software, with the top 6 biological pathways selected based on P-value and gene percentage, shown using bar graphs. Pā€‰<ā€‰0.05 was statistically significant. c Validation of the results of enrichment analysis of the differential immune-related genes using metascape software, a total of 20 pathways were enriched, shown using bar graphs. pā€‰<ā€‰0.05 was statistically significant. d Hallmarks gene set base used to analyse the entire gene expression values of LN and HC smaples. Significant enrichment in the interferon alpha pathway is shown, pā€‰<ā€‰0.05. e Hallmarks gene set database used to analyze the entire gene expression value of LN and HC samples. Shows significant enrichment in the interferon gamma pathway. pā€‰<ā€‰0.05

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