Fig. 1

Identification of potential immune subtypes of sarcoma. A Sample clustering heatmap of the 251 samples in the cohort from TCGA. B Sample clustering heatmap of the 287 samples in the cohort from GEO. C Kaplan–Meier curves with log-rank test showing the PFS of the sarcoma IMS in TCGA. D, E Distribution of IMS1-IMS3 across sarcoma (D) sex and (E) histological subtypes in TCGA. *P < 0.05. F Kaplan–Meier curves with log-rank test showing the PFS of sarcoma IMS in GSE21050. G, H Distribution ratio of IMS1-IMS3 across sarcoma (G) histological subtypes and (H) CINSARC subtypes in GSE21050. *P < 0.05. NA corresponds to data for which the chi-square test cannot be applied, such as a group of samples is 0. DDLPS, dedifferentiated liposarcoma; DT, desmoid tumor; LMS, leiomyosarcoma; MFS, myxofibrosarcoma; MPNST, malignant peripheral nerve sheath tumor; SS, synovial sarcoma; UPS, undifferentiated pleomorphic sarcoma