Fig. 3

Association between immune subtypes and chemotherapy-induced immune response-related classic markers and immune checkpoint genes. A, B Differential expression of immune subtypes and classic chemotherapy-induced immune response-related markers among the sarcoma immune subtypes in the cohorts from TCGA (A) and GSE21050 (B). C, D Differential expression of immune checkpoint-related genes among the sarcoma immune subtypes in TCGA (C) and GSE21050 (D). The top and bottom of the box are the upper quartile (Q3) and the lower quartile (Q1) of the data, respectively. The solid line in the box represents the median. The whiskers represent the maximum and minimum values of this group of data. The Kruskal–Wallis test was used to assess significant differences. ns, not significant, *P < 0.01, **P < 0.001, ***P < 0.0001, and ****P < 0.00001