Fig. 1

Subtypes of peripheral monocytes in patients with AGN. Peripheral blood was collected from healthy controls (n = 9), kidney-function adjusted controls (n = 9), patients with active AGN (n = 14) and patients with remissive AGN (n = 13). Samples were analyzed by flow cytometry to investigate proportion of different subtypes of cells including iNOS⁺CD68⁺, CD206⁺CD68⁺ and CD163⁺CD68⁺ cells. A A representative flow cytometry analysis of iNOS⁺CD68⁺ cells, CD206⁺CD68⁺ cells and CD163⁺CD68⁺ cells in peripheral blood of one individual from each group. B Histograms showed the proportions of different cells from each group. Dots represented for the number of proportions of iNOS⁺CD68⁺, CD206⁺CD68⁺ and CD163⁺CD68⁺ cells from each group and error bars represented for the standard deviation (SD). Compared with other groups, patients with active AGN presented with high proportion of CD206⁺CD68⁺ cells (p < 0.001). Patients with remissive AGN had higher proportion of CD206⁺CD68⁺ cells in comparison with healthy controls with statistical significance (p < 0.01). #p < 0.01; ##p < 0.001