Table 3 Clinico-pathological characteristics of HNSCC patients enrolled in the study of T cell profile

Age (years)

61.2 ± 15.8 (27–88)

Gender

 Male

28 (71.8%)

 Female

11 (28.2%)

Tumor Type

 Larynx

17 (43.6%)

 Tongue (from oral cavity)

22 (56.4%)

Lymph node (LN) Status(greatest dimension, cm)

 N0 (free LNs)

24 (61.5%)

 N1 (≤ 3)

4 (10.3%)

 N2 (> 3–6)

9 (23.1%)

 N3 (> 6)

1 (2.6%)

 Unknown

1 (2.6%)

Tumor size

 T1

4 (10.3%)

 T2

12 (30.8%)

 T3

15 (38.5%)

 T4

7 (17.9%)

 Unknown

1(2.6%)

Stage

 I

4 (10.3%)

 II

9 (23.1%)

 III

10 (25.6%)

 IV

15 (38.5%)

 Unknown

1 (2.6%)

Histological grade*

 Well differentiated (I)

19 (48.7%)

 Moderately differentiated (II)

15 (38.5%)

 Poorly differentiated (III)

3 (7.7%)

 Unknown

2 (5.1%)

Perineural/lymphovascular invasion

 Positive

8 (20.5%)

 Negative

30 (76.9%)

 Unknown

1 (2.6%)

Lymph nodes characteristic

 MLNs

11 (28.2%)

 nMLNs

24 (61.5%)

 Not determined

4 (10.3%)