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Fig. 7 | BMC Immunology

Fig. 7

From: Combined application of dinitrofluorobenzene and ovalbumin induced AD-like dermatitis with an increase in helper T-cell cytokines and a prolonged Th2 response

Fig. 7

Sensitization and induction protocol. Mice were randomly divided into four groups, listed as below. Control group (n = 4): mice were given solvent or saline, no hapten, allergen or drugs were given to them. DNFB only group (n = 4): DNFB(100ul each time) and saline were given to them,5 times in total for each single week. DNFB + OVA group (n = 8): DNFB and OVA were alternately given to the mice 5 times in total for each week, four mice of this group were euthanized at day14 (acute phase) by cervical dislocation, the other four mice were euthanized by the same way at day28 (chronic phase). OVA only group (n = 4): OVA and solvent were alternately given to the mice 5 times in total each week

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