Fig. 5
From: HIV specific Th1 responses are altered in Ugandans with HIV and Schistosoma mansoni coinfection
Association of frequency of CD8 T cells expressing cytolytic granules and S. mansoni infection among HIV + SM+ coinfected individuals. Comparison of the frequency of Granzymes K, A, B & perforin expressing CD8 T cells between HIV + SM + and HIV + SM − in response to separate GAG PTE POOL-1 and 2 stimulations. GAG PTE POOL-1 and GAG PTE POOL-2 responses were added together in the analysis. The horizontal line shows the mean and the vertical line shows the 95% confidence interval. Student’s t test and the Holm-Å Ãdák correction for multiple comparisons were used to compare the mean frequencies of CD8 T cells with cytotoxic potential between HIV + SM + and HIV + SM−. Twelve HIV + SM + and 12 HIV + SM − participants were stimulated with GAG PTE POOL-1 and GAG PTE POOL-2.