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Fig. 3 | BMC Immunology

Fig. 3

From: Immune cell profiles of idiopathic inflammatory myopathy patients expressed anti-aminoacyl tRNA synthetase or anti-melanoma differentiation-associated gene 5 autoantibodies

Fig. 3

IIM patients with anti-MDA5 autoantibody have a higher Th17 cell population in the pheripheral blood. Flow cytometry analyses of CD3, CD4, CXCR3, CCR6, and CCR4 surface markers in PBMCs of IIM patients with anti-aminoacyl-tRNA synthetase (ARS + , n = 36), or with anti-MDA5 antibody (MDA5 + , n = 22), and healthy controls (HC, n = 60). A One represented data was shown. Th1, CXCR3 + CD4 + ; Th2, CXCR3-CCR4 + CCR6-CD4 + ; Th9, CXCR3-CCR4-CCR6 + CD4 + ; and Th17 cells, CXCR3-CCR4 + CCR6 + CD4 + . B Each dot was displayed for each data from the enrolled subjects. Data are presented as means ± SD. The p values were calculated using Kruskal–Wallis test between the MDA5, ARS, and HC groups. ns, not significant

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BMC Immunology

ISSN: 1471-2172

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