Edited by Francesco Pappalardo, Giulia Russo and Marzio Pennisi.
Conformational flexibility of a free and TCR-bound pMHC-I protein investigated by long-term molecular dynamics simulations
Major histocompatibility complexes (MHCs) play a crucial role in the cell-mediated adaptive immune response as they present antigenic peptides (p) which are recognized by host T cells through a complex formati...