Significant Parameters | Group | Potential Result of Changes | |
---|---|---|---|
NK cell | ↓ CD56dimCD16− CD2+ | M v S | Impaired ability to adhere to target cells [24]. |
↓ CD56dimCD16− CD18+CD2+ | M v S | Reduced NK cells in an active state hence lessened NK cell activation and cytotoxic activity [24, 55]. | |
↑ CD56dimCD16− CD18+CD11c− | S v C | Decreased adhesive abilities or lower number of activated cells [55]. | |
↓ CD56brightCD16dim NKp46 | S v C, S v M | Reduced recognition and lysis of target cells [41]. | |
↓ Total SLAM | S v M | Lessened ability of NK cells to undergo cytotoxic activity [40]. | |
CD4+ T cell | ↑ Total KIR2DL5 | M v S | Inhibition of T cell functions [51]. |
↓ Naïve KLRG1 | M v C, M v S | Enhanced T cell activation [46]. | |
↑ Central Memory BTLA4 | M v C | Greater inhibitory signalling and modulation of immune responses [52]. | |
CD8+ T cell | ↑ CD45RA Effector Memory | M v C | Heightened capacity for cytotoxic activities [43]. |
↓ Central Memory LFA-1 | M v C | Lack of LFA-1 adhesion required for optimal cytotoxic activity [53]. | |
↓ Total KLRG1 | M v C | Enhanced T cell activation [46]. |