Fig. 4

Domain Predictions for Protein Variants of Targeted Genes (HHLA1,2 & 3 and MAGEB5). This figure shows the different domains identified for the targeted protein variants of related genes (HHLA1,2 & 3 and MAGEB5). The superfamily Polyhydroxyalkanoates domain (PHA03247) was identified for the two protein variants for HHLA1 though at different amino acid positions. Six out of the 7 protein variants for HHLA2 demonstrated Immunoglobulin V-set domain (pfam07686) common to antibodies and three superfamily Immunoglobulin C1-set domains (pfam07654) and superfamily Immunoglobulin domains (cl11960) found in HERV-H LTR-associating 2. One HHLA2 variant identified with one Immunoglobulin V-set, one superfamily Immunoglobulin C1-set and one superfamily Immunoglobulin domains. For MAGEB5, MAGE Homology Domain (MHD) (pfam01454) was identified on the only protein variant