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Fig. 4 | BMC Immunology

Fig. 4

From: ThPOK inhibits the immune escape of gastric cancer cells by inducing STPG1 to inactivate the ERK pathway

Fig. 4

STPG1 inhibits the immune escape of gastric cancer cells. A STPG1 expression in gastric cancer cells posttransfection of OE-STPG1 or OE-NC was detected by RT-qPCR. B CCK-8 assay was conducted to assess the viability of gastric cancer cells with overexpression of STPG1. C and D Flow cytometry analysis was used to detect the percentage of proliferated CD3+ T cells and the proportion of IFN-γ+ T cells after co-culture with gastric cancer cells (HGC-27, SNU-1) which were transfected with STPG1 overexpression vectors. *p < 0.05, **p < 0.01, ***p < 0.001

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