Fig. 6

CD4.1 sequence polymorphism in O. cubifrons. The sequence of the first three coding exons of three variant O. cubifrons cd4.1 alleles are shown in (A). Bars above the alignment indicate exon position, and shaded nucleotides indicate polymorphic sites. Black circles above the polymorphic positions indicate synonymous sites, red squares indicate non-synonymous sites. The protein sequences encoded by the first three exons of the variant cd4.1 alleles are shown in (B). Polymorphic amino acids are shaded, and a consensus sequence logo is shown underneath the alignment. The location of the signal peptide and Ig-like fold domain predicted by InterProScan is indicated above the alignment; shaded bars indicate the exons encoding the corresponding amino acids