Skip to main content

Articles

Page 16 of 20

  1. Immunosuppression by gliomas contributes to tumor progression and treatment resistance. It is not known when immunosuppression occurs during tumor development but it likely involves cross-talk among tumor cell...

    Authors: Benjamin C Kennedy, Lisa M Maier, Randy D'Amico, Christopher E Mandigo, Elizabeth J Fontana, Allen Waziri, Marcela C Assanah, Peter Canoll, Richard CE Anderson, David E Anderson and Jeffrey N Bruce

    Citation: BMC Immunology 2009 10:11

    Content type: Research article

    Published on:

  2. Viral infection and neoplastic transformation trigger endoplasmic reticulum (ER) stress. Thus, a large proportion of the cells that must be recognized by the immune system are stressed cells. Cells respond to ...

    Authors: Diana P Granados, Pierre-Luc Tanguay, Marie-Pierre Hardy, Étienne Caron, Danielle de Verteuil, Sylvain Meloche and Claude Perreault

    Citation: BMC Immunology 2009 10:10

    Content type: Research article

    Published on:

  3. Recognition of pathogens by dendritic cells (DCs) through interaction with pattern recognition receptors, including Toll like receptors (TLR), is crucial for the initiation of appropriate polarized T helper (T...

    Authors: Elly van Riet, Bart Everts, Kim Retra, Marion Phylipsen, Jaap J van Hellemond, Aloysius GM Tielens, Desiree van der Kleij, Franca C Hartgers and Maria Yazdanbakhsh

    Citation: BMC Immunology 2009 10:9

    Content type: Research article

    Published on:

  4. Zebrafish may prove to be one of the best vertebrate models for innate immunology. These fish have sophisticated immune components, yet rely heavily on innate immune mechanisms. Thus, the development and chara...

    Authors: Lora Petrie-Hanson, Claudia Hohn and Larry Hanson

    Citation: BMC Immunology 2009 10:8

    Content type: Research article

    Published on:

  5. Enprocal is a high-protein micro-nutrient rich formulated supplementary food designed to meet the nutritional needs of the frail elderly and be delivered to them in every day foods. We studied the potential of...

    Authors: Jagat R Kanwar and Rupinder K Kanwar

    Citation: BMC Immunology 2009 10:7

    Content type: Research article

    Published on:

  6. OK-432, penicillin-killed Streptococcus pyogenes, is used in treating lymphangiomas and carcinomas. We have studied in vitro the role of mononuclear phagocytes (MNPs), including purified monocytes (MOs), in the i...

    Authors: Carla Olsnes, Helen Stavang, Karl Brokstad, Jan Olofsson and Hans J Aarstad

    Citation: BMC Immunology 2009 10:6

    Content type: Research article

    Published on:

  7. CD4+CD25+ regulatory T cells play an essential role in maintaining immune homeostasis and preventing autoimmunity. Therefore, defects in Treg development, maintenance or function have been associated with several...

    Authors: Marta Barreto, Ricardo C Ferreira, Lara Lourenço, Maria F Moraes-Fontes, Eugénia Santos, Miguel Alves, Cláudia Carvalho, Berta Martins, Rita Andreia, João F Viana, Carlos Vasconcelos, Luísa Mota-Vieira, Carlos Ferreira, Jocelyne Demengeot and Astrid M Vicente

    Citation: BMC Immunology 2009 10:5

    Content type: Research article

    Published on:

  8. Normal mammary gland contains an extravascular population of B lymphoblasts, precursors of the immunoglobulin plasma cells that play a key role in the passive protection of neonates by secreting immunoglobulin...

    Authors: Berardo de Jesus Rodriguez, Claire Chevaleyre, Gwénaële Henry, Daniel Mollé, Isabelle Virlogeux-Payant, Mustapha Berri, François Boulay, Joëlle Léonil, François Meurens and Henri Salmon

    Citation: BMC Immunology 2009 10:4

    Content type: Research article

    Published on:

  9. Human B lymphocytes can produce leukotriene B4 but the biological function of the 5-lipoxygenase (5-LO) pathway in B cells is unclear. In order to better understand and define the role of 5-LO in B cells, we inve...

    Authors: Yilmaz Mahshid, Marcus-René Lisy, Xiao Wang, Rainer Spanbroek, Jenny Flygare, Birger Christensson, Magnus Björkholm, Birgitta Sander, Andreas JR Habenicht and Hans-Erik Claesson

    Citation: BMC Immunology 2009 10:2

    Content type: Research article

    Published on:

  10. Tumor-associated accrual of myeloid derived suppressor cells (MDSC) in the blood, lymphoid organs and tumor tissues may lead to perturbation of the arginine metabolism and impairment of the endogenous antitumo...

    Authors: Giusy Capuano, Nicolò Rigamonti, Matteo Grioni, Massimo Freschi and Matteo Bellone

    Citation: BMC Immunology 2009 10:1

    Content type: Research article

    Published on:

  11. Interferon induced tetratricopeptide repeat protein 2 (IFIT-2, P54) belongs to the type I interferon response genes and is highly induced after stimulation with LPS. The biological function of this protein is ...

    Authors: Susanne Berchtold, Birgit Manncke, Juliane Klenk, Julia Geisel, Ingo B Autenrieth and Erwin Bohn

    Citation: BMC Immunology 2008 9:75

    Content type: Research article

    Published on:

  12. The functional immaturity of T cells contributes to the susceptibility of neonates to infections and the less severe graft-versus-host disease associated with cord blood (CB) transplantation. We have previousl...

    Authors: Helen KW Law, Wenwei Tu, Enmei Liu and Yu Lung Lau

    Citation: BMC Immunology 2008 9:74

    Content type: Research article

    Published on:

  13. Asthma is a complicated network of inflammatory reactions. It is classified into mild, moderate, and severe persistent asthma. The success of asthma therapy relies much on understanding the underlying mechanis...

    Authors: AS Abdulamir, RR Hafidh, F Abubakar and KA Abbas

    Citation: BMC Immunology 2008 9:73

    Content type: Research article

    Published on:

  14. Chemokines immobilized on endothelial cells play a central role in the induced firm adhesion and transendothelial migration of leukocytes. Activation of platelets at sites of vascular injury is considered to s...

    Authors: Christian Weingart, Peter J Nelson, Bernhard K Krämer and Matthias Mack

    Citation: BMC Immunology 2008 9:72

    Content type: Research article

    Published on:

  15. Human CD1d-restricted, invariant natural killer T cells (iNKT) are a unique class of T lymphocytes that recognise glycolipid antigens such as α-galactosylceramide (αGalCer) and upon T cell receptor (TCR) activ...

    Authors: Joanne E Croudace, Stuart M Curbishley, Manuela Mura, Carrie R Willcox, Petr A Illarionov, Gurdyal S Besra, David H Adams and David A Lammas

    Citation: BMC Immunology 2008 9:71

    Content type: Research article

    Published on:

  16. Pro-inflammatory cytokines can affect intracellular lipid metabolism. A variety of effects have been described for different cell types; hepatocyte lipid turnover pathways are inhibited during inflammation, wh...

    Authors: Jenny Persson, Jan Nilsson and Marie W Lindholm

    Citation: BMC Immunology 2008 9:70

    Content type: Research article

    Published on:

  17. While dendritic cells (DCs) can induce tolerance in T cells, little is known about tolerance induction in DCs themselves. We have analysed tolerance induced in human in-vitro generated DCs by repeated stimulation...

    Authors: Valerie Albrecht, Thomas PJ Hofer, Brian Foxwell, Marion Frankenberger and Loems Ziegler-Heitbrock

    Citation: BMC Immunology 2008 9:69

    Content type: Research article

    Published on:

  18. There is increasing evidence to suggest an immunomodulation function both within the intestines and systemically upon consuming probiotic species. We recently isolated a novel LAB, Lactobacillus casei Zhang (LcZh...

    Authors: Tuo Ya, Qijin Zhang, Fuliang Chu, Justin Merritt, Menhe Bilige, Tiansong Sun, Ruiting Du and Heping Zhang

    Citation: BMC Immunology 2008 9:68

    Content type: Research article

    Published on:

  19. Bacillus anthracis secretes several virulence factors targeting different host organs and cell types during inhalational anthrax infection. The bacterial expression of a key virulence factor, lethal toxin (LeTx) ...

    Authors: Christopher Bradburne, Myung-Chul Chung, Qin Zong, Karen Schlauch, Derong Liu, Taissia Popova, Anna Popova, Charles Bailey, Dan Soppet and Serguei Popov

    Citation: BMC Immunology 2008 9:67

    Content type: Research article

    Published on:

  20. The ELR+CXC chemokines are multifunctional mediators that are mainly responsible for the recruitment of leucocytes to sites of inflammation and infection. Because of their high sequence identity with mammalian IL...

    Authors: Cai Zhonghua, Gao Chunpin, Zhang Yong, Xing Kezhi and Zhang Yaou

    Citation: BMC Immunology 2008 9:66

    Content type: Research article

    Published on:

  21. Mammals are essentially born germ-free but the epithelial surfaces are promptly colonized by astounding numbers of bacteria soon after birth. The most extensive microbial community is harbored by the distal in...

    Authors: Tomas Hrncir, Renata Stepankova, Hana Kozakova, Tomas Hudcovic and Helena Tlaskalova-Hogenova

    Citation: BMC Immunology 2008 9:65

    Content type: Research article

    Published on:

  22. IFN-γ is a multifunctional peptide with a potent immune defense function which is also known as a prototypic Th1 cytokine. While screening for genes differentially expressed by Th1 and Th2 cytokines, human thi...

    Authors: Seol-Hee Kim, Jiyoung Oh, Ja-Young Choi, Ji-Young Jang, Myoung-Wha Kang and Choong-Eun Lee

    Citation: BMC Immunology 2008 9:64

    Content type: Research article

    Published on:

  23. Ion channels are involved in the control of membrane potential (ψ) in a variety of cells. The maintenance of ψ in human T lymphocytes is essential for T-cell activation and was suggested to depend mostly on th...

    Authors: Fernanda Mello de Queiroz, Cristiano G Ponte, Adriana Bonomo, Rosane Vianna-Jorge and Guilherme Suarez-Kurtz

    Citation: BMC Immunology 2008 9:63

    Content type: Methodology article

    Published on:

  24. Deer mice (Peromyscus maniculatus) are among the most common mammals in North America and are important reservoirs of several human pathogens, including Sin Nombre hantavirus (SNV). SNV can establish a life-long ...

    Authors: Tiffany Richens, Aparna D~N Palmer, Joseph Prescott and Tony Schountz

    Citation: BMC Immunology 2008 9:62

    Content type: Research article

    Published on:

  25. Bv8, prokineticin-1, or endocrine gland-vascular endothelial growth factor, and prokineticin-2 are recently isolated peptide agonists of two G protein-coupled receptors, prokineticin receptor-1 (PROKR 1) and P...

    Authors: Silvia Franchi, Elisa Giannini, Donatella Lattuada, Roberta Lattanzi, Hui Tian, Pietro Melchiorri, Lucia Negri, Alberto E Panerai and Paola Sacerdote

    Citation: BMC Immunology 2008 9:60

    Content type: Research article

    Published on:

  26. The statistical analysis of immunological data may be complicated because precise quantitative levels cannot always be determined. Values below a given detection limit may not be observed (nondetects), and data w...

    Authors: Hae-Won Uh, Franca C Hartgers, Maria Yazdanbakhsh and Jeanine J Houwing-Duistermaat

    Citation: BMC Immunology 2008 9:59

    Content type: Methodology article

    Published on:

  27. Transglutaminases (TGases) form a group of enzymes that have many different substrates and among the most well known are fibrin for Factor XIIIa and the clotting protein in crustaceans. We also found that TGas...

    Authors: Xionghui Lin, Kenneth Söderhäll and Irene Söderhäll

    Citation: BMC Immunology 2008 9:58

    Content type: Research article

    Published on:

  28. The USDA, Wildlife Services cooperative oral rabies vaccination (ORV) program uses a live vaccinia virus-vectored (genus Orthopoxvirus) vaccine, Raboral V-RG® (V-RG), to vaccinate specific wildlife species agains...

    Authors: J Jeffrey Root, Robert G McLean, Dennis Slate, Kathleen A MacCarthy and Jorge E Osorio

    Citation: BMC Immunology 2008 9:57

    Content type: Research article

    Published on:

  29. Cytokine-stimulated endothelial cells (EC) propagate hematopoietic progenitor cell (HPC) expansion. However, the effects on the functional capacities of cultured progenitors have not been evaluated. HPC were a...

    Authors: Anja Moldenhauer, Gesche Genter, Andreas Lun, Gürkan Bal, Holger Kiesewetter and Abdulgabar Salama

    Citation: BMC Immunology 2008 9:56

    Content type: Research article

    Published on:

  30. We performed initial cell, cytokine and complement depletion studies to investigate the possible role of these effectors in response to vaccination with heat-killed Burkholderia mallei in a susceptible BALB/c mou...

    Authors: Gregory C Whitlock, Roman A Lukaszewski, Barbara M Judy, Slobodan Paessler, Alfredo G Torres and D Mark Estes

    Citation: BMC Immunology 2008 9:55

    Content type: Research article

    Published on:

  31. Dendritic cells (DCs) are antigen presenting cells capable of inducing innate and adaptive immune responses. According to the stimulus and their maturation state, DCs induce immunogenic or tolerogenic response...

    Authors: Hind Hamzeh-Cognasse, Fabrice Cognasse, Sabine Palle, Patricia Chavarin, Thomas Olivier, Olivier Delézay, Bruno Pozzetto and Olivier Garraud

    Citation: BMC Immunology 2008 9:54

    Content type: Research article

    Published on:

  32. CD8+ regulatory T cells (Treg) have been considered to be involved in a model of ocular-induced tolerance, known as anterior chamber-associated immune deviation (ACAID). The phenotype and characteristics of CD8+T...

    Authors: Hao He, Peizeng Yang, Liqiong Jiang, Junfeng Zhang, Changlin Zhao, Lina Chen, Xiaomin Lin, Hongyan Zhou and Aize Kijlstra

    Citation: BMC Immunology 2008 9:53

    Content type: Research article

    Published on:

  33. Streptococcus pneumoniae is a human pathogenic bacteria and a major cause of severe invasive diseases, including pneumonia, bacteremia, and meningitis. Infections with S. pneumoniae evoke a strong inflammatory re...

    Authors: Trine H Mogensen, Randi S Berg, Lars Østergaard and Søren R Paludan

    Citation: BMC Immunology 2008 9:52

    Content type: Research article

    Published on:

  34. Type I diabetes (TID) is an autoimmune disease resulting from destruction of the insulin-producing β-cells by autoreactive T cells. Studies have shown that polymorphisms of chemokine CXCL12 gene are linked to ...

    Authors: Qibin Leng, Yuchun Nie, Yongrui Zou and Jianzhu Chen

    Citation: BMC Immunology 2008 9:51

    Content type: Research article

    Published on:

  35. Amplification and cloning of naïve T cell Receptor (TR) repertoires or antigen-specific TR is crucial to shape immune response and to develop immuno-based therapies. TR variable (V) regions are encoded by seve...

    Authors: Ilenia Boria, Diego Cotella, Irma Dianzani, Claudio Santoro and Daniele Sblattero

    Citation: BMC Immunology 2008 9:50

    Content type: Methodology article

    Published on:

  36. Interleukin 1 beta (IL-1β) plays an important role in a number of chronic and acute inflammatory diseases. To understand the role of IL-1β in disease processes and develop an in vivo screening system for anti-inf...

    Authors: Limei Li, Zhaoliang Fei, Jianke Ren, Ruilin Sun, Zhihui Liu, Zhejin Sheng, Long Wang, Xia Sun, Jun Yu, Zhugang Wang and Jian Fei

    Citation: BMC Immunology 2008 9:49

    Content type: Research article

    Published on:

  37. The lung is divided into two major compartments: the alveolar space and the parenchyma. The alveolar macrophages are the first line of leukocytes in the lung taking up incoming microbes or microbial antigens w...

    Authors: Kapilan Kugathasan, Elizabeth K Roediger, Cherrie-Lee Small, Sarah McCormick, Pingchang Yang and Zhou Xing

    Citation: BMC Immunology 2008 9:48

    Content type: Research article

    Published on:

  38. Interleukin-17 (IL-17)-producing cells are increasingly considered to be the major pathogenic population in various autoimmune disorders. The effects of glucocorticoids, widely used as therapeutics for inflamm...

    Authors: Miljana Momčilović, Željka Miljković, Dušan Popadić, Miloš Marković, Emina Savić, Zorica Ramić, Djordje Miljković and Marija Mostarica-Stojković

    Citation: BMC Immunology 2008 9:47

    Content type: Research article

    Published on:

  39. Melioidosis, a lethal tropical infection that is endemic in southeast Asia and northern Australia, is caused by the saprophytic Gram-negative bacterium Burkholderia pseudomallei. Overall mortality approaches 40% ...

    Authors: T Eoin West, Robert K Ernst, Malinka J Jansson-Hutson and Shawn J Skerrett

    Citation: BMC Immunology 2008 9:46

    Content type: Research article

    Published on:

  40. Human mast cell (HuMC) maturation occurs in tissues interfacing with the external environment, exposing both mast cell progenitors and mature mast cells, to bacteria and their products. It is unknown, however,...

    Authors: Arnold S Kirshenbaum, Emily Swindle, Marianna Kulka, Yalin Wu and Dean D Metcalfe

    Citation: BMC Immunology 2008 9:45

    Content type: Research article

    Published on:

  41. The differentiation of naive T and B cells into memory lymphocytes is essential for immunity to pathogens. Therapeutic manipulation of this cellular differentiation program could improve vaccine efficacy and t...

    Authors: W Nicholas Haining, Jill Angelosanto, Kathleen Brosnahan, Kenneth Ross, Cynthia Hahn, Kate Russell, Linda Drury, Stephanie Norton, Lee Nadler and Kimberly Stegmaier

    Citation: BMC Immunology 2008 9:44

    Content type: Methodology article

    Published on:

  42. To evaluate the impact of the duration of chronic inflammation on gene expression in skeletal muscle biopsies (MBx) from untreated children with juvenile dermatomyositis (JDM) and identify genes and biological...

    Authors: Yi-Wen Chen, Rongye Shi, Nicholas Geraci, Sheela Shrestha, Heather Gordish-Dressman and Lauren M Pachman

    Citation: BMC Immunology 2008 9:43

    Content type: Research article

    Published on:

  43. CD4+CD25high regulatory T (TReg) cells modulate antigen-specific T cell responses, and can suppress anti-viral immunity. In HTLV-1 infection, a selective decrease in the function of TReg cell mediated HTLV-1-tax ...

    Authors: Jakob Michaëlsson, Hugo Marcelo R Barbosa, Kimberley A Jordan, Joan M Chapman, Milena KC Brunialti, Walter Kleine Neto, Youko Nukui, Ester C Sabino, Marco Antonio Chieia, Acary Souza Bulle Oliveira, Douglas F Nixon and Esper G Kallas

    Citation: BMC Immunology 2008 9:41

    Content type: Research article

    Published on:

  44. Toll-like receptor 2 (TLR2) plays a critical role in mediating inflammatory/immune responses against bacterial pathogens in lung. Streptococcus pneumoniae (S. pneumoniae) and nontypeable Haemophilus influenzae (N...

    Authors: Jae Hyang Lim, Unhwan Ha, Akihiro Sakai, Chang-Hoon Woo, Soo-Mi Kweon, Haidong Xu and Jian-Dong Li

    Citation: BMC Immunology 2008 9:40

    Content type: Research article

    Published on:

  45. Human B cells and plasmacytoid dendritic cells (pDC) are the only cells known to express both TLR7 and TLR9. Plasmacytoid dendritic cells are the primary IFN-α producing cells in response to TLR7 and TLR9 agon...

    Authors: John A Hanten, John P Vasilakos, Christie L Riter, Lori Neys, Kenneth E Lipson, Sefik S Alkan and Woubalem Birmachu

    Citation: BMC Immunology 2008 9:39

    Content type: Research article

    Published on:

  46. The greatest challenges in vaccine development include optimization of DNA vaccines for use in humans, creation of effective single-dose vaccines, development of delivery systems that do not involve live virus...

    Authors: Rogério S Rosada, Lucimara Gaziola de la Torre, Fabiani G Frantz, Ana PF Trombone, Carlos R Zárate-Bladés, Denise M Fonseca, Patrícia RM Souza, Izaíra T Brandão, Ana P Masson, Édson G Soares, Simone G Ramos, Lúcia H Faccioli, Célio L Silva, Maria HA Santana and Arlete AM Coelho-Castelo

    Citation: BMC Immunology 2008 9:38

    Content type: Research article

    Published on:

  47. Enteric antimicrobial peptides secreted from Paneth cells, including α-defensins (in mice named cryptdins), are key effector molecules of innate immunity in the small intestine. The importance of Paneth cells ...

    Authors: Jenny Karlsson, Katrin Pütsep, Hiutung Chu, Robert J Kays, Charles L Bevins and Mats Andersson

    Citation: BMC Immunology 2008 9:37

    Content type: Research article

    Published on:

Featured videos

View featured videos from across the BMC-series journals

Annual Journal Metrics

  • Speed
    92 days to first decision for reviewed manuscripts only
    64 days to first decision for all manuscripts
    182 days from submission to acceptance
    17 days from acceptance to publication

    Citation Impact
    2.495 - 2-year Impact Factor
    2.598 - 5-year Impact Factor
    0.683 - SNIP (Source-Normalized Impact per Paper)
    0.971 - SJR (SCImago Journal Rank)

    Usage 
    409,405 Downloads
    64 Altmetric Mentions