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1171 result(s) for 'immunology' within BMC Immunology

Page 7 of 24

  1. Hoxa9 is a homeodomain transcription factor important for the generation of Flt3+hiIL-7R- lymphoid biased-multipotential progenitors, Flt3+IL-7R+ common lymphoid progenitors (CLPs), and B cell precursors (BCP)...

    Authors: Kimberly Gwin, Joseph J Dolence, Mariya B Shapiro and Kay L Medina
    Citation: BMC Immunology 2013 14:5
    Content type: Research article Published on:

  2. Acute graft-versus-host disease (aGVHD) is one of the most common causes of morbidity for patients undergoing allogeneic stem cell transplantation. There is preliminary evidence that activated Group 2 innate l...

    Authors: Anand Srinivasan, Sandra Bajana, Aneta Pankow, Carrie Yuen, Rikin K. Shah and Xiao-Hong Sun
    Citation: BMC Immunology 2021 22:46
    Content type: Research Published on:

  3. Surgical intervention-related trauma contributes largely to the development of postoperative immunosuppression, with reduced resistance to secondary bacterial infection. This study compared the impact of lapar...

    Authors: Shun Gen Huang, Yi Ping Li, Qi Zhang, H Paul Redmond, Jiang Huai Wang and Jian Wang
    Citation: BMC Immunology 2013 14:27
    Content type: Research article Published on:

  4. Experimental studies in humans have yielded evidence that adaptive immune function, including the production of antigen-specific antibodies, is distinctly impaired when sleep is deprived at the time of first a...

    Authors: Christian Benedict, Maria Brytting, Agneta Markström, Jan-Erik Broman and Helgi Birgir Schiöth
    Citation: BMC Immunology 2012 13:1
    Content type: Research article Published on:

  6. Preconception allergen immunization prevents neonatal allergen sensitization in mice by a complex interaction between regulatory cells/factors and antibodies. The present study assessed the influence of matern...

    Authors: Jefferson R Victor, Bruno P Muniz, Ana E Fusaro, Cyro A de Brito, Eliana F Taniguchi, Alberto JS Duarte and Maria N Sato
    Citation: BMC Immunology 2010 11:11
    Content type: Research article Published on:

  8. Nasal polyp constitutes a benign growth process in the nasal and sinus mucosa. RCAS1 (receptor-binding cancer antigen expressed on SiSo cells) is a protein expressed mainly by various human cancer cells. It is...

    Authors: Magdalena Dutsch-Wicherek, Romana Tomaszewska, Pawel Strek, Lukasz Wicherek and Jacek Skladzien
    Citation: BMC Immunology 2006 7:4
    Content type: Research article Published on:

  9. Currently, research on the quantitative distribution of ABO antigens in different organs and tissues remains limited. We aimed to examine the individual characteristics of blood group glycoprotein A and B anti...

    Authors: Xianding Wang, Fan Zhang, Yamei Jiang, Zilin Xu, Xiaobing Feng, Linde Li, Yu Fan, Turun Song, Yunying Shi, Zhongli Huang and Tao Lin
    Citation: BMC Immunology 2021 22:66
    Content type: Research Published on:

  10. Lung cavitation is associated with heightened TB transmission and poor treatment outcomes. This study aimed to determine the relationship between systemic inflammation and lung cavitation in drug-resistant TB ...

    Authors: Thando Glory Maseko, Slindile Ngubane, Marothi Letsoalo, Santhuri Rambaran, Derseree Archary, Natasha Samsunder, Rubeshan Perumal, Surie Chinappa, Nesri Padayatchi, Kogieleum Naidoo and Aida Sivro
    Citation: BMC Immunology 2023 24:26
    Content type: Research Published on:

  11. Patients infected with Vibrio vulnificus (V. vulnificus) show severe inflammatory responses characterised by the upregulation of proinflammatory cytokines. Macrophage migration inhibitory factor (MIF), an upstrea...

    Authors: Chia-Chang Chuang, Yin-Ching Chuang, Wen-Teng Chang, Chi-Chung Chen, Lien-I Hor, A-Ming Huang, Pui-Ching Choi, Chi-Yun Wang, Po-Chin Tseng and Chiou-Feng Lin
    Citation: BMC Immunology 2010 11:50
    Content type: Research article Published on:

  12. Asthma is a common chronic airway disease in the world. The purpose of this study was to explore the expression of IL1-RL1 in sputum and its correlation with Th1 and Th2 cytokines in asthma.

    Authors: Changyi Xu, Lijuan Du, Fengjia Chen, Kun Tang, Lu Tang, Jia Shi, Lisha Xiao, Zhimin Zeng, Yuxia Liang and Yubiao Guo
    Citation: BMC Immunology 2022 23:23
    Content type: Research Published on:

  13. TCR and CXCR4-mediated signaling appears to be reciprocally regulated pathways. TCR activation dampens the chemotactic response towards the CXCR4 ligand CXCL12, while T cells exposed to CXCL12 are less prone t...

    Authors: Jacob Ngai, Marit Inngjerdingen, Torunn Berge and Kjetil Taskén
    Citation: BMC Immunology 2009 10:27
    Content type: Research article Published on:

  14. While dealing with mixed in vitro lymphocyte cultures one is faced with the problem of relative contributions of different populations to the activity being studied. This is especially true in the controversy rel...

    Authors: R Nirmala and PR Narayanan
    Citation: BMC Immunology 2002 3:9
    Content type: Research article Published on:

  15. An accurate test for Mycobacterium tuberculosis infection is urgently needed in immunosuppressed populations. The aim of this study was to investigate the diagnostic power of enzyme-linked immunospot (ELISPOT)-ba...

    Authors: Weimin Jiang, Lingyun Shao, Ying Zhang, Shu Zhang, Chengyan Meng, Yunya Xu, Lingli Huang, Yun Wang, Ying Wang, Xinhua Weng and Wenhong Zhang
    Citation: BMC Immunology 2009 10:31
    Content type: Research article Published on:

  16. Impaired spermatozoa immunogenicity can result in pregnancy complications such as recurrent spontaneous abortion (RSA). Given that spermatozoa contact with microbiota, it is possible that inappropriate microbi...

    Authors: Mitra Rafiee, Nasrin Sereshki, Razieh Alipour, Vahid Ahmadipanah, Davod Pashoutan Sarvar and David Wilkinson
    Citation: BMC Immunology 2022 23:32
    Content type: Research Published on:

  17. We aimed to report the clinical characteristics, immunological features, and treatment of one patient with a de novo STAT3 gain-of-function mutation identified by next generation sequencing. We investigated th...

    Authors: Wenjie Wang, Luyao Liu, Xiaoying Hui, Ying Wang, Wenjing Ying, Qinhua Zhou, Jia Hou, Mi Yang, Bijun Sun, Jinqiao Sun and Xiaochuan Wang
    Citation: BMC Immunology 2021 22:19
    Content type: Research article Published on:

  18. Evidence is accumulating that chronic inflammation may have an important role in prostate cancer (PCa). The COX-2 polymorphism rs2745557 (+202 C/T) has been extensively investigated as a potential risk factor ...

    Authors: Hongtuan Zhang, Yong Xu, Zhihong Zhang, Ranlu Liu and Baojie Ma
    Citation: BMC Immunology 2012 13:14
    Content type: Research article Published on:

  19. Streptococcus sanguinis (S.sanguinis), a predominant bacterium in the human oral cavity, has been widely associated with the development of infective endocarditis. Platelets play both a haemostatic function and c...

    Authors: Fabrice Cognasse, Hind Hamzeh-Cognasse, Adrien Chabert, Elke Jackson, Charles-Antoine Arthaud, Olivier Garraud and Archie McNicol
    Citation: BMC Immunology 2014 15:15
    Content type: Research article Published on:

  20. Inflammatory bowel disease (IBD) is thought to be due to an abnormal interaction between the host immune system and commensal microflora. Within the intestinal immune system, B cells produce physiologically na...

    Authors: Caterina Defendenti, Piercarlo Sarzi-Puttini, Silvia Grosso, Annamaria Croce, Olivia Senesi, Simone Saibeni, Simona Bollani, Piero Luigi Almasio, Savino Bruno and Fabiola Atzeni
    Citation: BMC Immunology 2011 12:71
    Content type: Research article Published on:

  21. Prostaglandin E2 (PGE2) is an endogenous lipid mediator of inflammation. Its production is regulated by the rate-limiting upstream enzyme cyclooxygenase-2 (COX-2). We have recently demonstrated that the major cel...

    Authors: Whajung Cho and Jongseon Choe
    Citation: BMC Immunology 2020 21:20
    Content type: Research article Published on:

  22. Inflammasomes are a group of molecules that are strongly involved in causing inflammation. This study aimed to evaluate the expression of NLR family pyrin domain containing 1 (NLRP1), NLRP3, and Apoptosis-asso...

    Authors: Zahra Bagheri-Hosseinabadi, Ali Shamsizadeh, Fatemeh Bahrehmand and Mitra Abbasifard
    Citation: BMC Immunology 2023 24:30
    Content type: Research Published on:

  23. Interleukin-33 is a member of the IL-1 cytokine family whose functions are mediated and modulated by the ST2 receptor. IL-33-ST2 expression and interactions have been explored in mouse macrophages but little i...

    Authors: Amrita D Joshi, Sameer R Oak, Adam J Hartigan, William G Finn, Steven L Kunkel, Karen E Duffy, Anuk Das and Cory M Hogaboam
    Citation: BMC Immunology 2010 11:52
    Content type: Research article Published on:

  24. Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease affecting different organ systems. This study aimed to determine the concentrations of 30 different human cytokines, chemokines, and growth fa...

    Authors: Laila A. Damiati, Iuliana Denetiu, Sami Bahlas, Samar Damiati and Peter Natesan Pushparaj
    Citation: BMC Immunology 2023 24:13
    Content type: Research Published on:

  25. Intestinal mucus production by hyperplasic goblet cells is a striking pathological feature of many parasitic helminth infections and is related to intestinal protection and worm expulsion. Induction of goblet ...

    Authors: Reece G Marillier, Chesney Michels, Elizabeth M Smith, Lizette CE Fick, Mosiuoa Leeto, Benjamin Dewals, William GC Horsnell and Frank Brombacher
    Citation: BMC Immunology 2008 9:11
    Content type: Research article Published on:

  26. Determining T cell responses to naturally processed and presented antigens is a critical immune correlate to determine efficacy of an investigational immunotherapeutic in clinical trials. In most cases, minima...

    Authors: Jay Friedman, Sreenivasulu Gunti, Maxwell Lee, Ke Bai, Christian Hinrichs and Clint T. Allen
    Citation: BMC Immunology 2022 23:5
    Content type: Research Published on:

  27. The immune system is particularly sensitive to stress. Although acute stress generally has positive effects, chronic stress typically provokes immunosuppression. The elucidation of the mechanisms involved in i...

    Authors: Lourdes Domínguez-Gerpe and Manuel Rey-Méndez
    Citation: BMC Immunology 2001 2:7
    Content type: Research article Published on:

  28. Serious infections are common in patients undergoing autologous stem cell transplantation (ASCT) mainly because of the effects of immunosuppression. The innate immune system plays an important role in the defe...

    Authors: Ana Moreto, Concepción Fariñas-Alvarez, Maria Puente, Javier Gonzalo Ocejo-Vinyals, Pablo Sánchez-Velasco, Juan Pablo Horcajada, Ana Batlle, Carmen Montes, Francisca Santos, Eulogio Conde and Maria-Carmen Fariñas
    Citation: BMC Immunology 2014 15:17
    Content type: Research article Published on:

  29. Allergen immunotherapy (SIT) is the only treatment for allergic disease capable of modifying disease long term. To reduce the risk of anaphylaxis from SIT, allergen-extracts have been modified by polymerisatio...

    Authors: Zoe L Urry, David F Richards, Cheryl Black, Maria Morales, Jerónimo Carnés, Catherine M Hawrylowicz and Douglas S Robinson
    Citation: BMC Immunology 2014 15:21
    Content type: Research article Published on:

  30. BKPyV associated hemorrhagic cystitis (BKPyV-HC) is a major and prevalent outcome of hematopoietic stem cell transplantation (HSCT) with no standard treatment option. Adoptive T cell therapy (ACT) against tran...

    Authors: Maryam Mohammadi Najafabadi, Masoud Soleimani, Mohammad Ahmadvand, Mina Soufi Zomorrod and Seied Asadollah Mousavi
    Citation: BMC Immunology 2022 23:31
    Content type: Research Published on:

  32. Leukocyte recruitment across blood vessels is fundamental to immune surveillance and inflammation. Lymphocyte homing to peripheral lymph nodes is mediated by the adhesion molecule, L-selectin, which binds to s...

    Authors: Jiwei Yang, Steven D Rosen, Philip Bendele and Stefan Hemmerich
    Citation: BMC Immunology 2006 7:12
    Content type: Research article Published on:

  34. Host genetic variations may contribute to disease susceptibility of influenza. IL-1A and IL-1B are important inflammatory cytokines that mediate the inflammation and initiate the immune response against virus ...

    Authors: Yingxia Liu, Shaoyuan Li, Guoliang Zhang, Guang Nie, Zhizhong Meng, Dongting Mao, Chang Chen, Xinchun Chen, Boping Zhou and Gucheng Zeng
    Citation: BMC Immunology 2013 14:37
    Content type: Research article Published on:

  35. Activin A is a pleiotrophic regulatory cytokine, the ablation of which is neonatal lethal. Healthy human alveolar macrophages (AMs) constitutively express activin A, but AMs of patients with pulmonary alveolar...

    Authors: Heidi Dalrymple, Barbara P Barna, Anagha Malur, Achut G Malur, Mani S Kavuru and Mary Jane Thomassen
    Citation: BMC Immunology 2013 14:41
    Content type: Research article Published on:

  37. Recent studies have demonstrated a protective role for IL-33 against obesity-associated inflammation, atherosclerosis and metabolic abnormalities. IL-33 promotes the production of T helper type 2 (Th2) cytokin...

    Authors: Amal Hasan, Fahad Al-Ghimlas, Samia Warsame, Asma Al-Hubail, Rasheed Ahmad, Abdullah Bennakhi, Monira Al-Arouj, Kazem Behbehani, Mohammed Dehbi and Said Dermime
    Citation: BMC Immunology 2014 15:19
    Content type: Research article Published on:

  38. Immune checkpoint inhibitors have aroused great expectation of tumor eradication. However, the effect of anti-PD-L1 treatment for cervical cancer is unsatisfactory and the underlying antagonist to anti-PD-L1 e...

    Authors: Fengying Xu, Fengying Zhang, Qian Wang, Ying Xu, Shuifang Xu, Caihong Zhang and Lihua Wang
    Citation: BMC Immunology 2021 22:60
    Content type: Research Published on:

  39. Cow antibodies are very unusual in having exceptionally long CDR H3 regions. The genetic basis for this length largely derives from long heavy chain diversity (DH) regions, with a single “ultralong” DH, IGHD8–...

    Authors: Brevin A. Smider and Vaughn V. Smider
    Citation: BMC Immunology 2020 21:30
    Content type: Research article Published on:

  40. Chronic immune activation and hyperglycaemia are a hallmark of type 2 diabetes mellitus (T2D) while natural killer (NK) cells are involved in the pathogenesis of T2D. Dysregulated NK cell responses are associa...

    Authors: Vuyolwethu Mxinwa, Phiwayinkosi V. Dludla, Tawanda M. Nyambuya, Kabelo Mokgalaboni, Sithandiwe E. Mazibuko-Mbeje and Bongani B. Nkambule
    Citation: BMC Immunology 2020 21:51
    Content type: Research article Published on:

  41. Alveolar macrophages are one of the first lines of defence against invading pathogens and play a central role in modulating both the innate and acquired immune systems. By responding to endogenous stimuli with...

    Authors: Paul J Groot-Kormelink, Lindsay Fawcett, Paul D Wright, Martin Gosling and Toby C Kent
    Citation: BMC Immunology 2012 13:57
    Content type: Research article Published on:

  42. Circulating memory T cells can be divided into tissue-specific subsets, which traffic through distinct tissue compartments during physiologic immune surveillance, based on their expression of adhesion molecule...

    Authors: Pia Kivisäkk, Barbara Tucky, Tao Wei, James J Campbell and Richard M Ransohoff
    Citation: BMC Immunology 2006 7:14
    Content type: Research article Published on:

  43. The recruitment of lymphocytes to secondary lymphoid organs relies on interactions of circulating cells with high endothelial venules (HEV). HEV are exclusive to these organs under physiological conditions, bu...

    Authors: José L Pablos, Begoña Santiago, Durwin Tsay, Mark S Singer, Guillermo Palao, María Galindo and Steven D Rosen
    Citation: BMC Immunology 2005 6:6
    Content type: Research article Published on:

  45. Recombinant Mycobacterium bovis bacille Calmette–Guèrin (rBCG) expressing three T cell epitopes of Mycobacterium tuberculosis (MTB) Ag85B antigen (P1, P2, P3) fused to the Mtb8.4 protein (rBCG018) or a combinatio...

    Authors: Rohimah Mohamud, Maryam Azlan, Daniel Yero, Nadine Alvarez, Maria E Sarmiento, Armando Acosta and Mohd-Nor Norazmi
    Citation: BMC Immunology 2013 14(Suppl 1):S5
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 14 Supplement 1

  46. Lipid rafts have been shown to play a role in T cell maturation, activation as well as in the formation of immunological synapses in CD4+ helper and CD8+ cytotoxic T cells. However, the differential expression of...

    Authors: Valeria de Mello Coelho, Dzung Nguyen, Banabihari Giri, Allyson Bunbury, Eric Schaffer and Dennis D Taub
    Citation: BMC Immunology 2004 5:2
    Content type: Research article Published on:

  47. Various microbial, inflammatory and immune signals regulate the activation of dendritic cells (DC), determining their ability to interact with naïve T cells and to produce cytokines that direct T cell developm...

    Authors: Amy Wesa and Anne Galy
    Citation: BMC Immunology 2002 3:14
    Content type: Research article Published on:

  48. Glucocorticoids are the first-line treatment for Pemphigus vulgaris (PV), but its serious side effects can be life-threatening for PV patients. Tacrolimus (FK506) has been reported to have an adjuvant treatmen...

    Authors: Zhimin Xie, Xiangnong Dai, Qingqing Li, Sifan Lin and Xingdong Ye
    Citation: BMC Immunology 2023 24:43
    Content type: Research Published on:

  49. It is well established that adaptive immune responses induced by hypercholesterolemia play an important role in the development of atherosclerosis, but the pathways involved remain to be fully characterized. I...

    Authors: Daniel Kolbus, Ornélia H Ramos, Katarina E Berg, Josefin Persson, Maria Wigren, Harry Björkbacka, Gunilla Nordin Fredrikson and Jan Nilsson
    Citation: BMC Immunology 2010 11:58
    Content type: Research article Published on:

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