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1173 result(s) for 'immunology' within BMC Immunology

Page 14 of 24

  1. Immune cells and cytokines have been linked to viremia dynamic and immune status during HIV infection. They may serve as useful biomarkers in the monitoring of people living with HIV-1 (PLHIV-1). The present w...

    Authors: Yaou Pierrot Assogba, Adefounke Prudencia Adechina, Edmond Tchiakpe, Odilon Paterne Nouatin, René K. Kèkè, Moussa Bachabi, Honoré Sourou Bankole and Akadiri Yessoufou
    Citation: BMC Immunology 2024 25:22
    Content type: Research Published on:

  2. The interaction between the Leishmania parasite and the host cell involves complex, multifaceted processes. The disease severity in cutaneous leishmaniasis (CL) is largely dependent on the causative species. Most...

    Authors: Gajendra Kumar Katara, Anand Raj, Rajesh Kumar, Kumar Avishek, Himanshu Kaushal, Nasim Akhtar Ansari, Ram Awatar Bumb and Poonam Salotra
    Citation: BMC Immunology 2013 14:52
    Content type: Research article Published on:

  3. Toxic shock syndrome (TSS) is caused by an overwhelming host-mediated response to bacterial superantigens produced mainly by Staphylococcus aureus and Streptococcus pyogenes. TSS is characterized by aberrant acti...

    Authors: Hani Kim, Ilyse Darwish, Maria-Fernanda Monroy, Darwin J Prockop, W Conrad Liles and Kevin C Kain
    Citation: BMC Immunology 2014 15:1
    Content type: Research article Published on:

  4. Patients with indolent B-cell non-Hodgkin lymphomas (B-NHLs) have an increased risk of infections which is caused by pathomechanisms of the diseases itself but also as a result of anti-tumor therapy. Especiall...

    Authors: Christoph Lutz, Stefan Feiten, Geothy Chakupurakal, Jochen Heymanns, Jörg Thomalla, Christoph van Roye and Rudolf Weide
    Citation: BMC Immunology 2023 24:2
    Content type: Research Published on:

  5. The ICOS-B7h costimulatory receptor-ligand pair is required for germinal center formation, the production of isotype-switched antibodies, and antibody affinity maturation in response to T cell-dependent antige...

    Authors: Kevin Larimore, Linda Liang, Sonia Bakkour and William C Sha
    Citation: BMC Immunology 2012 13:29
    Content type: Research article Published on:

  6. Mast cells have recently gained new importance as immunoregulatory cells that are involved in numerous pathological processes. One result of these processes is an increase in mast cell numbers at peripheral si...

    Authors: Maria Célia Jamur, Andréa N Moreno, Luciana FC Mello, Devandir A Souza Júnior, Maria Rita C Campos, Maria Verônica D Pastor, Ana Cristina G Grodzki, Deise C Silva and Constance Oliver
    Citation: BMC Immunology 2010 11:32
    Content type: Research article Published on:

  7. The use of immunotherapy strategies for the treatment of advanced cancer is rapidly increasing. Most immunotherapies rely on induction of CD8+ tumor-specific cytotoxic T cells that are capable of directly kill...

    Authors: Samantha S. Beauford, Anita Kumari and Charlie Garnett-Benson
    Citation: BMC Immunology 2020 21:18
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Immunology 2020 21:36

  8. Experimental analyses have identified strain-dependent factors that regulate susceptibility to anaphylaxis in mice. We assessed the susceptibility of the widely used 129SvEvBrd (also known as 129S5) mouse stra...

    Authors: Muthuvel Arumugam, Richard Ahrens, Heather Osterfeld, Leah C Kottyan, Xun Shang, John A Maclennan, Nives Zimmermann, Yi Zheng, Fred D Finkelman and Simon P Hogan
    Citation: BMC Immunology 2011 12:14
    Content type: Research article Published on:

  9. In holoendemic Plasmodium falciparum transmission areas such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb) < 6.0 g/dL, with any density parasitemia] is the most common clinical manifestation of s...

    Authors: Winnie A Okeyo, Elly O Munde, Wilson Okumu, Evans Raballah, Samuel B Anyona, John M Vulule, John M Ong’echa, Douglas J Perkins and Collins Ouma
    Citation: BMC Immunology 2013 14:15
    Content type: Research article Published on:

  10. The significance of a unique inhibitory Fc receptor for IgG, FcγRIIB (RIIB), in the prevention of spontaneous production of autoantibodies remains controversial, due mainly to the fact that the RIIB locus is adja...

    Authors: Yasuyoshi Kanari, Akiko Sugahara–Tobinai, Haruka Takahashi, Masanori Inui, Akira Nakamura, Sachiko Hirose and Toshiyuki Takai
    Citation: BMC Immunology 2014 15:47
    Content type: Research article Published on:

  11. Antibody isotype responses can be useful as indicators of immune bias during infection. In studies of parasite co-infection however, interpretation of immune bias is complicated by the occurrence of cross-reac...

    Authors: Karen J Fairlie-Clarke, Tracey J Lamb, Jean Langhorne, Andrea L Graham and Judith E Allen
    Citation: BMC Immunology 2010 11:6
    Content type: Research article Published on:

  13. One of the major obstacles in the design of an effective vaccine against HIV-1 is the hypervariability of the HIV-1 envelope glycoprotein. Most HIV-1 vaccine candidates have utilized envelope glycoprotein from...

    Authors: Ali Azizi, David E Anderson, Masoud Ghorbani, Katrina Gee and Francisco Diaz-Mitoma
    Citation: BMC Immunology 2006 7:25
    Content type: Research article Published on:

  14. The inflammasome is an intracellular protein complex triggered by exposure to intracellular pathogens, its components or other endogenous proteins. It leads to the activation of and subsequent release of proin...

    Authors: Hanna K De Jong, Gavin CKW Koh, Miriam HP van Lieshout, Joris JTH Roelofs, Jaap T van Dissel, Tom van der Poll and W Joost Wiersinga
    Citation: BMC Immunology 2014 15:30
    Content type: Research article Published on:

  16. Human B lymphocytes can produce leukotriene B4 but the biological function of the 5-lipoxygenase (5-LO) pathway in B cells is unclear. In order to better understand and define the role of 5-LO in B cells, we inve...

    Authors: Yilmaz Mahshid, Marcus-René Lisy, Xiao Wang, Rainer Spanbroek, Jenny Flygare, Birger Christensson, Magnus Björkholm, Birgitta Sander, Andreas JR Habenicht and Hans-Erik Claesson
    Citation: BMC Immunology 2009 10:2
    Content type: Research article Published on:

  17. Growing knowledge about cellular interactions in the immune system, including the central role of cytokine networks, has lead to new treatments using monoclonal antibodies that block specific components of the...

    Authors: Wilco de Jager, Katarzyna Bourcier, Ger T Rijkers, Berent J Prakken and Vicki Seyfert-Margolis
    Citation: BMC Immunology 2009 10:52
    Content type: Research article Published on:

  18. The Eph receptors are the largest receptor tyrosine kinase family. Several family members are expressed in hematopoietic cells. Previously, the expression of a member of this family, EphA2, was identified on d...

    Authors: Else Munthe, Eivind Farmen Finne and Hans-Christian Aasheim
    Citation: BMC Immunology 2004 5:9
    Content type: Research article Published on:

  19. It is well established that PD-1 is expressed by follicular T cells but its function in regulation of human T helper cells has been unclear. We investigated the expression modality and function of PD-1 express...

    Authors: Chuanwu Wang, Peter Hillsamer and Chang H Kim
    Citation: BMC Immunology 2011 12:53
    Content type: Research article Published on:

  20. Allergen recognition by dendritic cells (DCs) is a key event in the allergic cascade leading to production of IgE antibodies. C-type lectins, such as the mannose receptor and DC-SIGN, were recently shown to pl...

    Authors: Inas K Sharquie, Abeer Al-Ghouleh, Patricia Fitton, Mike R Clark, Kathryn L Armour, Herb F Sewell, Farouk Shakib and Amir M Ghaemmaghami
    Citation: BMC Immunology 2013 14:54
    Content type: Research article Published on:

  21. This report describes a method for the generation of global gene expression profiles from low frequent B-cell subsets by using fluorescence-activated cell sorting and RNA amplification. However, some of the di...

    Authors: Kim Steve Bergkvist, Mette Nyegaard, Martin Bøgsted, Alexander Schmitz, Julie Støve Bødker, Simon Mylius Rasmussen, Martin Perez-Andres, Steffen Falgreen, Anders Ellern Bilgrau, Malene Krag Kjeldsen, Michael Gaihede, Martin Agge Nørgaard, John Bæch, Marie-Louise Grønholdt, Frank Svendsen Jensen, Preben Johansen…
    Citation: BMC Immunology 2014 15:3
    Content type: Research article Published on:

  22. The association between lipid metabolism disorder and carcinogenesis is well-established, but there is limited research on the connection between lipid metabolism-related genes (LRGs) and lung adenocarcinoma (...

    Authors: Yi Yin, Muqun He, Yunjian Huang and Xianhe Xie
    Citation: BMC Immunology 2023 24:37
    Content type: Research Published on:

  23. At present, it is highly controversial whether pure mast cells can serve as antigen presenting cells, and it is not known whether the capacity of antigen presenting function is temporally restricted to a parti...

    Authors: Jian Gong, Ning-Sun Yang, Michael Croft, I-Chun Weng, Liangwu Sun, Fu-Tong Liu and Swey-Shen Chen
    Citation: BMC Immunology 2010 11:34
    Content type: Research article Published on:

  24. Despite the functions of TLRs in the parasitic infections have been extensively reported, few studies have addressed the role of TLR3 in the immune response to Schistosoma japonicum infections. The aim of this st...

    Authors: Hongyan Xie, Dianhui Chen, Yuanfa Feng, Feng Mo, Lin Liu, Junmin Xing, Wei Xiao, Yumei Gong, Shanni Tang, Zhengrong Tan, Guikuan Liang, Shan Zhao, Weiguo Yin and Jun Huang
    Citation: BMC Immunology 2024 25:2
    Content type: Research Published on:

  25. Expressed in embryonic development, matrix metalloprotein-9 (MMP-9) is absent in most of developed adult tissues, but recurs in inflammation during tissue injury, wound healing, tumor formation and metastasis....

    Authors: Ling Zhou, Chunli Yan, Roben G Gieling, Yujiro Kida, Warren Garner, Wei Li and Yuan-Ping Han
    Citation: BMC Immunology 2009 10:15
    Content type: Research article Published on:

  27. Numerous investigations have previously evaluated the association of interleukin (IL) 4 gene polymorphisms and the risk of asthma, conferring inconsistent results. To resolve the incongruent outcomes yielded from...

    Authors: Ahmad Kousha, Armita Mahdavi Gorabi, Mehdi Forouzesh, Mojgan Hosseini, Markov Alexander, Danyal Imani, Bahman Razi, Mohammad Javad Mousavi, Saeed Aslani and Haleh Mikaeili
    Citation: BMC Immunology 2020 21:55
    Content type: Research article Published on:

  28. This study was designed to investigate the role of the nucleotide-binding-domain -and leucine-rich repeat -containing (NLR) family, pyrin-domain-containing 3 (NLRP3) inflammasome in the pathogenesis of polymyo...

    Authors: Ping Xia, Yu-Quan Shao, Cong-Cong Yu, Yu Xie and Zhi-Jie Zhou
    Citation: BMC Immunology 2022 23:39
    Content type: Research Published on:

  29. Genetic polymorphisms observed in various disease states associated with sensitivity or resistance to specific treatments have been a robust area of investigation for decades, with the potential to allow clini...

    Authors: Yun-Ping Lim, Yu-An Hsu, Kun-Hsi Tsai, Fuu-Jen Tsai, Cheng-Yuan Peng, Wen-Ling Liao, Dong-Zong Hung, Ni Tien, Chien-Yih Lin and Lei Wan
    Citation: BMC Immunology 2013 14:21
    Content type: Research article Published on:

  30. Vitamin A (VA) deficiency induces a type 1 cytokine response and exogenously provided retinoids can induce a type 2 cytokine response both in vitro and in vivo. The precise mechanism(s) involved in this phenotypi...

    Authors: Harry D Dawson, Gary Collins, Robert Pyle, Michael Key, Ashani Weeraratna, Vishwa Deep-Dixit, Celeste N Nadal and Dennis D Taub
    Citation: BMC Immunology 2006 7:27
    Content type: Research article Published on:

  31. Multiple immune evasion strategies by which HCV establishes chronic infection have been proposed, including manipulation of cytokine responses. Prior infection with HIV increases the likelihood of chronic HCV ...

    Authors: Lisa Barrett, Maureen Gallant, Constance Howley, M Ian Bowmer, Geri Hirsch, Kevork Peltekian and Michael Grant
    Citation: BMC Immunology 2008 9:28
    Content type: Research article Published on:

  32. The CXCR3 receptor and its three interferon-inducible ligands (CXCL9, CXCL10 and CXCL11) have been implicated as playing a central role in directing a Th1 inflammatory response. Recent studies strongly support...

    Authors: Chung-Her Jenh, Mary Ann Cox, Long Cui, Eva-Pia Reich, Lee Sullivan, Shu-Cheng Chen, David Kinsley, Shiguang Qian, Seong Heon Kim, Stuart Rosenblum, Joseph Kozlowski, Jay S Fine, Paul J Zavodny and Daniel Lundell
    Citation: BMC Immunology 2012 13:2
    Content type: Research article Published on:

  33. Dendritic cells (DCs) play a crucial role in initiating effective cell-mediated immune responses, but are dysfunctional and anergic in breast cancer. Reversal of this dysfunction and establishment of optimal D...

    Authors: Sukchai Satthaporn, Mark M Aloysius, Richard A Robins, Chandan Verma, Suebwong Chuthapisith, Alasdair J Mckechnie, Mohamad El-Sheemy, Wichai Vassanasiri, David Valerio, David Clark, Jibril A Jibril and Oleg Eremin
    Citation: BMC Immunology 2008 9:32
    Content type: Research article Published on:

  34. Understanding the complex interactions of the immune response mediated by Mycobacterium tuberculosis and HIV co-infection is fundamental to disease biomarker discovery, vaccine, and drug development. Using flow c...

    Authors: Santhuri Rambaran, Thando Glory Maseko, Lara Lewis, Razia Hassan-Moosa, Derseree Archary, Sinaye Ngcapu, Nigel Garrett, Lyle R. McKinnon, Nesri Padayatchi, Kogieleum Naidoo and Aida Sivro
    Citation: BMC Immunology 2023 24:21
    Content type: Research Published on:

  35. Triggering receptor expressed on myeloid cells 2 (TREM2) signaling is considered to regulate anti-inflammatory responses in macrophages, dendritic cell maturation, osteoclast development, induction of obesity,...

    Authors: Hwa-Youn Lee, Eun-Hee Lee, Jawoon Yi, Kon-Young Ji, Su-Man Kim, Ha-Rim Choi, Su-Min Yee, Hyung-Sik Kang and Eun-Mi Kim
    Citation: BMC Immunology 2021 22:30
    Content type: Research Published on:

  36. T cells from HIV+ and aged individuals show parallels in terms of suppressed proliferative activity and interleukin-2 (I1-2) production and an increased number of CD8+ CD28- T cells. In order to compare cytokine ...

    Authors: Edward H Eylar, Carmen E Lefranc, Yasuhiro Yamamura, Ineabely Báez, Sol Luis Colón-Martinez, Nayra Rodriguez and T B Breithaupt
    Citation: BMC Immunology 2001 2:10
    Content type: Research article Published on:

  37. Human intestinal epithelial cells (IECs) secrete the chemokine CCL20 in response to infection by various enteropathogenic bacteria or exposure to bacterial flagellin. CCL20 recruits immature dendritic cells an...

    Authors: Shomik Sibartie, Ann M O'Hara, Jude Ryan, Áine Fanning, Jim O'Mahony, Shaun O'Neill, Barbara Sheil, Liam O'Mahony and Fergus Shanahan
    Citation: BMC Immunology 2009 10:54
    Content type: Research article Published on:

  38. Transforming growth factor beta (TGF-β) is a typical immuno-inhibitory cytokine and highly secreted by lung cancer cells. It was supposed that its immunosuppressive effects to NK cell might be related with the...

    Authors: Young Shin Lee, Hojung Choi, Hae-Ryung Cho, Woo-Chang Son, You-Soo Park, Chi-Dug Kang and Jaeho Bae
    Citation: BMC Immunology 2021 22:44
    Content type: Research Published on:

  39. Prolonged alcohol consumption is a significant co-factor in the progression of chronic viral infections including hepatitis C and HIV, which are both single-stranded RNA viruses. Toll like receptor 8 (TLR8), a...

    Authors: Maoyin Pang, Shashi Bala, Karen Kodys, Donna Catalano and Gyongyi Szabo
    Citation: BMC Immunology 2011 12:55
    Content type: Research article Published on:

  40. Primary immune thrombocytopenia (ITP) is characterized for the skewed Th differentiation towards Th1 and Th17 cells as well as the impaired number and function of regulatory T cells (Tregs). Tregs are capable ...

    Authors: Jingjing Cao, Yanxia Zhan, Lili Ji, Pu Chen, Luya Cheng, Feng Li, Xibing Zhuang, Zhihui Min, Lihua Sun, Fanli Hua, Hao Chen, Boting Wu and Yunfeng Cheng
    Citation: BMC Immunology 2023 24:6
    Content type: Research article Published on:

  41. Transient receptor potential ankyrin 1 (TRPA1) channels are known to be actively involved in various pathophysiological conditions, including neuronal inflammation, neuropathic pain, and various immunological ...

    Authors: Anukrishna Radhakrishnan, Tathagata Mukherjee, Chandan Mahish, P Sanjai Kumar, Chandan Goswami and Subhasis Chattopadhyay
    Citation: BMC Immunology 2023 24:16
    Content type: Research Published on:

  42. Understanding pathogenic mechanisms is imperative for developing novel treatment to the tuberculosis, an important public health burden worldwide. Recent studies demonstrated that host cholesterol levels have ...

    Authors: Jinrui Xu, Yanbing Zhou, Yi Yang, Cuiping Lv, Xiaoming Liu and Yujiong Wang
    Citation: BMC Immunology 2020 21:26
    Content type: Research article Published on:

  43. Immunization with recombinant carboxyl-terminal domain of the heavy chain (Hc domain) of botulinum neurotoxin (BoNT) stimulates protective immunity against native BoNT challenge. Most studies developing a botu...

    Authors: Beata Clapp, Sarah Golden, Massimo Maddaloni, Herman F Staats and David W Pascual
    Citation: BMC Immunology 2010 11:36
    Content type: Research article Published on:

  44. Human CD1d-restricted, invariant natural killer T cells (iNKT) are a unique class of T lymphocytes that recognise glycolipid antigens such as α-galactosylceramide (αGalCer) and upon T cell receptor (TCR) activ...

    Authors: Joanne E Croudace, Stuart M Curbishley, Manuela Mura, Carrie R Willcox, Petr A Illarionov, Gurdyal S Besra, David H Adams and David A Lammas
    Citation: BMC Immunology 2008 9:71
    Content type: Research article Published on:

  46. Immuno-epidemiologists are often faced with multivariate outcomes, measured repeatedly over time. Such data are characterised by complex inter- and intra-outcome relationships which must be accounted for durin...

    Authors: Lawrence Lubyayi, Patrice A. Mawa, Stephen Cose, Alison M. Elliott, Jonathan Levin and Emily L. Webb
    Citation: BMC Immunology 2021 22:63
    Content type: Methodology article Published on:

  49. The lymphatic vascular pattern in the head of mice has rarely been studied, due to problems of sectioning and immunostaining of complex bony structures. Therefore, the association of head lymphoid tissues with th...

    Authors: Melanie Lohrberg, Reinhard Pabst and Jörg Wilting
    Citation: BMC Immunology 2018 19:5
    Content type: Research article Published on:

  50. Toll-like receptor 4 (TLR4) is widely recognized as an essential element in the triggering of innate immunity, binding pathogen-associated molecules such as Lipopolysaccharide (LPS), and in initiating a cascad...

    Authors: Humberto M Garay-Malpartida, Roberta F Mourão, Marluce Mantovani, Icaro A Santos, Mari C Sogayar and Anna C Goldberg
    Citation: BMC Immunology 2011 12:18
    Content type: Research article Published on:

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BMC Immunology

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